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Keywords: Biomarker
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Cellular Physiology and Biochemistry (2019) 51 (6): 2704–2715.
Published Online: 12 December 2018
... needed. We aimed to identify potential long non-coding RNAs (lncRNAs) in circulatory exosomes that may serve as biomarkers for the detection of early-stage CRC. Methods: Exosomes from the plasma of CRC patients (n = 50) and healthy individuals (n = 50) were isolated by ultracentrifugation, followed...
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Cellular Physiology and Biochemistry (2018) 51 (5): 2010–2018.
Published Online: 06 December 2018
...Cheng Zhang; Yu Liang; Ming-Hui Ma; Kun-Zhe Wu; Chun-Dong Zhang; Dong-Qiu Dai Background/Aims: MicroRNAs have a significant role in the tumorigenesis and progression of cancers, including gastric cancer (GC). Our study aimed to identify a novel biomarker to predict the prognosis of patients with GC...
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Cellular Physiology and Biochemistry (2018) 51 (1): 290–300.
Published Online: 19 November 2018
... characterized. Methods: We investigated the levels of circRNAs in patients with HCC to identify potential diagnostic biomarkers. We examined circRNA expression profiles in liver tumors and paired non-cancerous liver tissues from three HCC patients with cancer thrombus using a circRNA microarray. Bioinformatics...
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Cellular Physiology and Biochemistry (2018) 50 (1): 66–78.
Published Online: 02 October 2018
... of this protein could be a clinically useful prognostic biomarker. xiaozhouhe123@163.com 8 01 2018 24 09 2018 2 10 2018 © 2018 The Author(s). Published by S. Karger AG, Basel 2018 Open Access License / Drug Dosage / Disclaimer This article is licensed under the Creative Commons...
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Cellular Physiology and Biochemistry (2018) 49 (3): 1048–1059.
Published Online: 07 September 2018
... Hepatocellular carcinoma Prognosis Biomarker Hepatocellular carcinoma (HCC) is the third most common malignancy worldwide and the second leading cause of cancer-related deaths [ 1 ]. The occurrence and development of HCC are associated with chronic hepatitis, alcoholism, and toxin-induced liver injury...
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Cellular Physiology and Biochemistry (2018) 49 (2): 816–827.
Published Online: 30 August 2018
...). However current diagnostic and therapeutic modalities against NSCLC are ineffective due to incomplete understanding of molecular pathogenesis of NSCLC. Emerging evidence shows that long non-coding RNAs (lncRNAs) can function as biomarkers for diagnosis and prognosis. LncRNAs can control transcription...
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Cellular Physiology and Biochemistry (2018) 48 (6): 2247–2257.
Published Online: 16 August 2018
... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Gastric cancer Adjuvant chemotherapy Genetic polymorphism Biomarker...
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Cellular Physiology and Biochemistry (2018) 48 (4): 1804–1814.
Published Online: 03 August 2018
... that hsa-miR-27b-3p (miR-27b) was up-regulated in KD serum. However, the specific role of miR-27b in KD remains unclear. We aimed to investigate that miR-27b could be a biomarker and therapeutic target for KD treatment. As well, the specific mechanism of miR-27b effecting endothelial cell functions...
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Cellular Physiology and Biochemistry (2018) 48 (3): 1177–1187.
Published Online: 25 July 2018
... reclassification index increased significantly after addition of CCN1 (23.9%, p =0.0179). Conclusions : CCN1 is strongly predictive of 6-month mortality in patients with AHF, suggesting serum CCN1 as a promising candidate prognostic biomarker for AHF patients. dongxg@mail.sysu.edu.cn 4 10 2017 6...
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Cellular Physiology and Biochemistry (2018) 48 (3): 1012–1018.
Published Online: 23 July 2018
... and 0.962 in training set and validation set respectively. Conclusions: Circulating XLOC_014172 and RP11-230G5.2 may act as novel biomarkers in GDM patients as fingerprint for the risk of macrosomia outcome. wxcz_0812@163.com 29 12 2017 25 05 2018 23 7 2018 © 2018 The Author(s...
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Cellular Physiology and Biochemistry (2018) 47 (6): 2369–2379.
Published Online: 10 July 2018
... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cerebrovascular Stroke Serum Uric acid Biomarker Association Stroke is a more common and frequently occurring disease in middle and old...
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Cellular Physiology and Biochemistry (2018) 47 (5): 2126–2135.
Published Online: 05 July 2018
... ], possibly indicating the reverse embryogenesis process occurs during tumorigenesis [ 21 ]. Breast cancer Let-7d Jab1 COPS5 CSN5 Biomarker Let-7 family, including let-7d, was reported to inhibit tumor pathogenesis [ 20, 22 ]. On the other hand, let-7d contributes to the pathogenesis of some...
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Cellular Physiology and Biochemistry (2018) 46 (6): 2508–2516.
Published Online: 05 May 2018
...Kewei Zhao; Qing Zhao; Zhaodi Guo; Zhixiang Chen; Yanwei Hu; Jing Su; Lian Chen; Zhiliang He; Xiuping Cai; Minyuan Chen; Lei Zheng; Wen Wang; Qian Wang Background/Aims: Circular RNAs (circRNAs) serve as potential diagnostic biomarkers. In this study, we aimed to identify a potential biomarker from...
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Cellular Physiology and Biochemistry (2018) 46 (5): 1939–1950.
Published Online: 26 April 2018
...Tao Wu; Yichen Chen; Yantao Du; Jin Tao; Zhong Zhou; Zhuo Yang Background/Aims: MicroRNAs (miRNAs) can be used as biomarkers for cardiovascular diseases, especially for heart failure. However, there are few reports on serum exosomal miRNA biomarkers in patients with acute heart failure (AHF) due...
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Cellular Physiology and Biochemistry (2018) 45 (5): 1904–1914.
Published Online: 02 March 2018
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Lncrna NNT-AS1 Osteosarcoma Biomarker Osteosarcoma is the most common primary malignancy of bone and frequently occurs in young adults and adolescents [ 1, 2...
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Cellular Physiology and Biochemistry (2018) 45 (3): 962–972.
Published Online: 02 February 2018
... ratio was 8.38 (95% CI: 6.86-10.25), and the overall area under the curve was 0.81 (95% CI: 0.77-0.84), indicating good discriminative ability of circRNAs as biomarkers for digestive system malignancy. Conclusion: circRNAs distinguish patients with digestive system cancer from controls with relatively...