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Keywords: BACE1
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Journal Articles
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Cellular Physiology and Biochemistry (2017) 42 (3): 1213–1226.
Published Online: 03 July 2017
.... Western blot and immunofluorescence were employed to detect the expression of β-site APP cleaving enzyme 1 (BACE1) and c-AMP response element-binding protein (CREB). Results: Learning and memory were significantly impaired in 2VO rats, and these changes were accompanied by neuronal loss and glial...
Journal Articles
Subject Area:
Further Areas
Cellular Physiology and Biochemistry (2014) 33 (1): 11–22.
Published Online: 02 January 2014
... of beta amyloid (Aβ) peptide following the abnormal proteolytic processing of amyloid precursor protein (APP) by β-secretase (BACE1) and γ-secretase. Accumulating evidence indicates that several microRNAs (miRNAs) are involved in the Alzheimer's disease (AD) by regulating the expression of APP and BACE1...