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Keywords: Auranofin
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Cellular Physiology and Biochemistry (2018) 45 (6): 2421–2430.
Published Online: 15 March 2018
... responses that ultimately lead to heart failure. Auranofin (Aur) has been used for treating rheumatic arthritis for several decades. Aur is a 19S proteasome-associated deubiquitinase inhibitor, and inhibition of the proteasome is speculated to reverse cardiac hypertrophy. However, the role...
Journal Articles
Subject Area:
Further Areas
Cellular Physiology and Biochemistry (2015) 37 (3): 1018–1028.
Published Online: 23 September 2015
...Kousi Alzoubi; Jasmin Egler; Majed Abed; Florian Lang Background/Aims: The antiinflammatory, antimicrobial and anticancer drug auranofin has previously been shown to trigger apoptosis, the suicidal death of nucleated cells. Side effects of the drug include anaemia. At least in theory the anaemia...