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Keywords: Astragaloside-IV
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Journal Articles

Astragaloside-IV Alleviates Heat-Induced Inflammation by Inhibiting Endoplasmic Reticulum Stress and Autophagy

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Zhiwei Dong, Jian Zhou, Ying Zhang, Yajie Chen, Zichen Yang, Guangtao Huang, Yu Chen, Zhiqiang Yuan, Yizhi Peng, Tongtong Cao
Journal: Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 42 (2): 824–837.
https://doi.org/10.1159/000478626
Published Online: 23 June 2017
... that triggers a series of induces pathological changes. However, this mechanism underlying heat-induced inflammation in thermal inhalation injury remains unclear. Studies have revealed that astragaloside-IV (AS-IV), a natural compound extracted from Astragalus membranaceus , has protective effects...
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Journal Articles

Astragaloside-IV Protects Against Heat-induced Apoptosis by Inhibiting Excessive Activation of Mitochondrial Ca 2+ Uniporter

Subject Area:
Further Areas
Zhiwei Dong, Chen Zhang, Yajie Chen, Yu Chen, Zhiqiang Yuan, Yizhi Peng, Tongtong Cao
Journal: Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 42 (2): 480–494.
https://doi.org/10.1159/000477595
Published Online: 05 June 2017
... investigated the MCU activity after heat treatment and assessed whether Astragaloside-IV (AS-IV) suppresses heat-induced apoptosis in bronchial epithelial cells by inhibiting the activation of the mitochondrial Ca 2+ uniporter (MCU), mitochondrial depolarisation and reactive oxygen species (ROS) production...
View article titled, <span class="search-highlight">Astragaloside</span>-<span class="search-highlight">IV</span> Protects Against Heat-induced Apoptosis by Inhibiting Excessive Activation of Mitochondrial Ca 2+ Uniporter
Open the PDF for <span class="search-highlight">Astragaloside</span>-<span class="search-highlight">IV</span> Protects Against Heat-induced Apoptosis by Inhibiting Excessive Activation of Mitochondrial Ca 2+ Uniporter in another window