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Keywords: Agonists
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Journal Articles
The Search for New Agonists to P2X7R for Clinical Use: Tuberculosis as a Possible Target
Open AccessRômulo J. Soares-Bezerra, Rosa T. Pinho, Rodrigo da C. Bisaggio, Thereza Christina Benévolo-de-Andrade, Luiz A. Alves
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2015) 37 (2): 409–418.
Published Online: 28 August 2015
... studies demonstrate the involvement of the P2X7 receptor (P2X7R) in the control of Mycobacterium tuberculosis (MTB) infection. Adenosine triphosphate (ATP), a natural agonist for P2X7R, promotes MTB death and the induction of apoptosis in monocytes and macrophages infected with MTB via activation of P2X7R...
