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Keywords: Adipogenesis
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Cellular Physiology and Biochemistry (2018) 51 (1): 154–172.
Published Online: 15 November 2018
... homeostasis. However, the underlying mechanisms are still not fully understood. Here, we investigated the effects of calcium supplementation on adipogenesis and glucose homeostasis in porcine bone marrow mesenchymal stem cells (pBMSCs) and high fat diet (HFD)-fed mice and explored the involved signaling...
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Cellular Physiology and Biochemistry (2018) 49 (6): 2254–2263.
Published Online: 26 September 2018
... of cardiac homeostasis and regeneration. However, the mechanism underlying the influence of diabetes on CSCs remains unclear. This study demonstrated that hyperglycemia might promote adipogenesis in CSCs, which induces a decline in myocardial regeneration capability in diabetes. Methods: CSCs were isolated...
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Cellular Physiology and Biochemistry (2018) 44 (6): 2467–2475.
Published Online: 18 December 2017
.... Activation patterns of MAPKs were assayed using protein microarray and Western blot. Three specific MAPK blockers, U0126, SB20358 and SP600125, were used to block ERK1/2, P38 and JNK during trans-differentiation. Cellular adipogenesis was measured using staining and morphological observations of cells...
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Cellular Physiology and Biochemistry (2018) 44 (5): 1762–1774.
Published Online: 06 December 2017
... to play a role in promoting autophagy. In this study, we investigated whether rapamycin participates in the survival and adipogenesis of ischemia-challenged adipose-derived stem cells (ADSCs) by regulating autophagy. Methods: Before the cells were exposed to oxygen-glucose deprivation (OGD), a simulated...
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Cellular Physiology and Biochemistry (2017) 42 (3): 1165–1176.
Published Online: 30 June 2017
...Jicui Chen; Huichen Zhao; Xiaoli Ma; Yuchao Zhang; Sumei Lu; Yangang Wang; Chen Zong; Dandan Qin; Yuanmei Wang; Yingfeng Yingfeng Yang; Xiangdong Wang; Yuantao Liu Background/Aims: The aim of this study was to determine the direct role of liraglutide (LG) in adipogenesis and lipid metabolism...
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Cellular Physiology and Biochemistry (2017) 41 (2): 484–500.
Published Online: 30 January 2017
... Background: BMP9 induces both osteogenic and adipogenic differentiation of mesenchymal stem cells (MSCs). Nell1 is a secretory glycoprotein with osteoinductive and anti-adipogenic activities. We investigated the role of Nell1 in BMP9-induced osteogenesis and adipogenesis in MSCs. Methods: Previously...
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Cellular Physiology and Biochemistry (2016) 40 (3-4): 681–692.
Published Online: 30 November 2016
...Lili Zhang; Mengmeng Liu; Xiaokang Zhou; Yi Liu; Bo Jing; Xiaogang Wang; Qi Zhang; Yao Sun Background/Aims: Bone marrow adipogenesis is one of the major characteristics of aged bone. Bone marrow mesenchymal stem cells (BMMSCs) prefer to differentiate into adipocytes instead of osteoblasts...
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Cellular Physiology and Biochemistry (2016) 39 (3): 1087–1097.
Published Online: 26 August 2016
...Renli Qi; Dingbiao Long; Jing Wang; Qi Wang; Xiaofeng Huang; Chunting Cao; Guangliang Gao; Jinxiu Huang Background/Aims: Muscle cells are able to trans-differentiate into adipocytes with adipogenesis induction. MicroRNAs (miRNAs), a class of small non-coding RNAs, widely participate...
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Journal Articles
Cellular Physiology and Biochemistry (2015) 37 (6): 2297–2310.
Published Online: 02 December 2015
... SL and occupational exposure to power frequency magnetic fields (MF), no mechanism has been proposed so far that explains an influence of these fields on adipogenesis. Methods: The study investigates the effects of a 50 Hz, 100 µT MF on the adipogenesis of stem cells isolated from human adipose...
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Cellular Physiology and Biochemistry (2015) 37 (1): 143–152.
Published Online: 17 August 2015
... effectively promoted osteogenesis and inhibited adipogenesis by simultaneously affecting the Wnt and Hh pathways. Conclusion: These results suggest that LiCl influences the differentiation of BMSCs directly through the Wnt and Hh pathways and thus may be a candidate drug for the treatment of osteoporosis...
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Cellular Physiology and Biochemistry (2015) 36 (4): 1499–1516.
Published Online: 06 July 2015
.... Adipogenesis Inflammation Insulin receptor Insulin-stimulated glucose uptake DNA methylation 3T3-L1 Hypertrophied and dysfunctional adipocytes from obese subjects lose their ability to respond to prolonged overnutrition and induce the secretion of several proinflammatory cytokines such as tumor...
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Cellular Physiology and Biochemistry (2012) 30 (2): 307–320.
Published Online: 22 June 2012
...Craig Younce; Pappachan Kolattukudy Obesity involves inflammation. MCP-1, an inflammatory chemokine, and MCP-1-induced protein (MCPIP) are known to induce adipogenesis that causes increase in the number of adipocytes. Here we elucidate the intermediate processes through which MCPIP induces...
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Cellular Physiology and Biochemistry (2007) 20 (6): 781–790.
Published Online: 30 October 2007
...-positive cells. AGRA-treated cells cultured in adipogenic differentiation medium could give rise to mature adipocytes that express both PPARγ and C/EBPα. The presence of AGRA during adipogenic differentiation did not inhibit adipogenesis of skeletal muscle cells. AGRA treatment did not affect Cx43...