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Keywords: Activation mechanism
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Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 49 (1): 359–367.
Published Online: 23 August 2018
... inflammasome signaling. Here, we have explored the activation mechanisms behind this process. NLRP3 is an intracellular receptor detecting factors ranging from the endogenous alarmins and adenosine triphosphate (ATP) to ultraviolet radiation and solid particles. Due to the plethora of triggers, the activation...