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Keywords: ΔF508 CFTR
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Journal Articles
Knockdown of NHERF1 Enhances Degradation of Temperature Rescued ΔF508 CFTR from the Cell Surface of Human Airway Cells
Available to PurchaseSubject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2007) 20 (6): 763–772.
Published Online: 30 October 2007
...Sang-Ho Kwon; Harvey Pollard; William B. Guggino ΔF508 CFTR can be functionally restored in the plasma membrane by exposure of the cell to lower temperature. However, restored ΔF508 CFTR has a much shorter half-life than normal. We studied whether NHERF1, which binds to the PDZ motif of CFTR, might...