... days before surgical drainage. However, permanent structural changes in the retina can occur within this timeframe. Suprachoroidal injection of recombinant tissue plasminogen activator (TPA) may speed up clot breakdown and aid early surgical drainage. We present a case series of macula-involving...

... a submacular hemorrhage (SMH), and a computerized tomography scan demonstrated a displaced orbital floor fracture with inferior rectus entrapment and a medial wall fracture. To induce displacement of the SMH, intravitreal injection of 0.25 μg tissue plasminogen activator (tPA) was combined with 0.3 mL...

... photograph acquired before t-PA injection. e Color fundus photograph acquired at 1 month after t-PA injection. f Color fundus photograph acquired at 3 months after t-PA injection. OCT, optical coherence tomography; t-PA, tissue plasminogen activator. Fig. 1. OCT and color fundus photographs acquired...

...Koichi Matsumoto; Celso Soiti Matsumoto; Kei Shinoda; Emiko Watanabe; Atsushi Mizota Purpose: To report a case of a ruptured eye with a suprachoroidal hemorrhage (SCH) in which tissue plasminogen activator (tPA)-assisted vitrectomy was successful in reconstructing the globe and restoring good...