Purpose: To report the first case of ophthalmia due to contact with cobra venom in the Volta Region, Ghana. Methods: An ointment containing vitamin A was applied to treat the patient’s unilateral defects in the corneal epithelium and the consequent diminished visual acuity. Results: Healing of the corneal epithelium and improvement of visual acuity were observed after only 1 day. Conclusions: This case suggests that consequences of cases of cobra venom spitting in the eyes can be minimal if immediate treatment is provided.

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