This study explored whether reactions to the Cancer Genetics Network (CGN) or CGN enrollment differed by receipt of a standard informational brochure versus a targeted version addressing factors previously associated with African Americans’ health behavior decisions and research participation. The 262 participants, identified through tumor registries or clinic contacts, were mailed brochures and completed phone interviews. When asked whether – based on the brochure – they were or were not ‘leaning toward’ CGN enrollment, about 75% of both standard and targeted groups reported leaning toward. When given the opportunity at the end of the interview, 68% enrolled in the CGN. Trust was strongly related to enrollment. Less education, less satisfaction with cancer care, and individualistic rather than collective orientation were associated with lower trust. Education was also bivariately associated with enrollment, but mediation analysis indicated that the operational mechanism of education’s influence on enrollment was through trust.

1.
Ard J, Skinner CS, Svetkey L: Acculturation and dietary intake among African American participants in the PREMIER trial. J Behav Med 2005;28:239–247.
2.
Hughes C, Peterson SK, Ramirez A, Gallion KJ, McDonald PG, Skinner CS, Bowen D: Minority recruitment in hereditary breast cancer research. Cancer Epidemiol Biomarkers Prev 2004;13:1146–1155.
3.
Kreuter M, Skinner C, Holt C, Clark E, Haire-Joshu D, Fu Q, Booker A, Steger-May K, Buckholtz D: Cultural tailoring for mammography and fruit and vegetable intake among low-income African American women in urban public health centers. Prev Med 2005;41:53–62.
4.
Bowen DJ, Vu T, Kasten-Sportes C: Increasing minority participant enrollment into a cancer family registry: the Cancer Genetics Network. Community Genet 2008;11:191–192.
5.
Moorman PG, Skinner CS, Evans JP, Newman B, Sorenson JR, Calingaert B, Susswein L, Crankshaw TS, Hoyo C, Schildkraut JM: Racial differences in enrolment in a cancer genetics registry. Cancer Epidemiol Biomarkers Prev 2004;13:1349–1354.
6.
Corbie-Smith G, Thomas SB, Williams MV, Moody-Ayers S: Attitudes and beliefs of African Americans toward participation in medical research. J Gen Intern Med 1999;14:537–546.
7.
Friemuth V, Quinn S, Thomas S, Cole G, Zook E, Duncan T: African Americans’ views on research and the Tuskegee Syphilis Study. Soc Sci Med 2001;52:797–808.
8.
Kass NE, Sugarman J, Faden R, Schoch-Spana M: Trust, the fragile foundation of contemporary biomedical research. Hastings Cent Rep 1996;26:25–29.
9.
Gamble K: Communication and information: the experience of radiotherapy patients. Eur J Cancer Care 1998;7:153–161.
10.
Mouton CP, Harris S, Rovi S, Solorzano P, Johnson MS: Barriers to black women’s participation in cancer clinical trials. J Natl Med Assoc 1997;89:721–727.
11.
Lukwago SN, Kreuter MW, Holt CL, Steger-May K, Bucholtz DC, Skinner CS: Sociocultural correlates of breast cancer knowledge and screening in urban African American women. Am J Pub Health 2003;93:1271–1274.
12.
Skinner C, Kreuter M, Buchanan A, Holt C, Buckholtz D: Adaptation of tailored intervention message libraries. Health Educ 2003;103:221–229.
13.
Lukwago SN, Kreuter MW, Bucholtz DC, Holt CL, Clark EM: Development and validation of brief scales to measure collectivism, religiosity, racial pride, and time orientation in urban African American women. Fam Community Health 2001;24:63–71.
14.
Hall MA, Dugan E, Zheng B, Mishra AK: Trust in physicians and medical institutions: what is it, can it be measured, and does it matter? Milbank Q 2001;79:613–639.
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