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Keywords: Tobramycin
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Journal Articles
Journal Articles
Chemotherapy (1993) 39 (3): 153–162.
Published Online: 11 September 2009
... to dicloxacillin the staphylococci were characterized by an increase in the number of crosswalls, rifampin produced thickening of the cell wall, but only minimal changes were induced by gentamicin. Intracellular electrondense aggregates were observed in P. aeruginosa after exposure to imipenem, tobramycin...
Journal Articles
Chemotherapy (1995) 41 (5): 330–333.
Published Online: 11 September 2009
... for the pulmonary deterioration in these patients. Tobramycin has variable inhibitory effects on these organisms, but in many isolates this inhibition is increased in vitro by exposure to the diuretic, amiloride. Aerosolized amiloride has been shown to be of clinical benefit in CF. The basis for this synergy...
Journal Articles
Chemotherapy (1997) 43 (2): 100–107.
Published Online: 11 September 2009
...Robert C. Cohn; Lois Rudzienski Antibiotic-resistant Burkholderia cepacia is an important pathogen in cystic fibrosis. We have previously shown enhanced tobramycin susceptibility of most strains in the presence of the drug amiloride. Others have shown similar findings in the presence of cationic...
Journal Articles
Chemotherapy (1989) 35 (4): 246–253.
Published Online: 09 September 2009
...Ashir Kumar; Rosslyn Wofford-McQueen; Ralph C. Gordon For 16 isolates of Pseudomonas cepacia from patients with cystic fibrosis, synergism was determined by the killing curve method, utilizing various combinations of antibiotics [ticarcillin (Ti), rifampin (Ri), tobramycin (To), imipenem (Im...
Journal Articles
Chemotherapy (1988) 34 (5): 361–366.
Published Online: 09 September 2009
...Milap C. Nahata The objective of this study was to assess the impact of intravenous infusion systems on the pharmacokinetic parameters of tobramycin in newborn infants. Thirty infants (gestational age 28–38 weeks; birth weight 0.8–3.5 kg; postnatal age 4–10 days) with presumed or proven gram...
Journal Articles
Chemotherapy (1989) 35 (1): 23–38.
Published Online: 09 September 2009
...Walter H Traub; Dierk Bauer; Marlene Spohr Five antimicrobial drugs (ceftazidime, ciprofloxacin, imipenem, piperacillin and tobramycin) and two human, intravenously applicable, IgG immunoglobulin preparations (Psomaglobin®, Polyglobin N®) were examined alone and in various combinations...
Journal Articles
Chemotherapy (1989) 35 (5): 360–362.
Published Online: 09 September 2009
...A. Kropec; F. Daschner The in vitro activity of the 4-quinolone compound fleroxacin (Ro-23–6240) was compared with that of enoxacin, ofloxacin, cefepime (BMY-28142), ceftazidime, ceftriaxone, and tobramycin against a total of 30 recent clinical isolates of Acinetobacter calcoaceticus subsp...
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Chemotherapy (1983) 29 (6): 385–394.
Published Online: 08 September 2009
...B. Olier; G. Viotte; J.P. Morin; J.P. Fillastre Many factors play a role in aminoglycoside nephrotoxicity. To study the influence of dosage regimens, Wistar rats were injected for 8 days with a total daily dose of 10, 20, or 50 mg/kg tobramycin intraperitoneally either in one single (1...
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Chemotherapy (1980) 26 (5): 354–360.
Published Online: 08 September 2009
...P. Sandven; J. Lassen; O. Solberg; Ø. Evandt The minimal inhibitory concentration for tobramycin and gentamicin against 488 clinical isolates of Enterobacteriaceae, Staphylococcus aureus and Pseudomonas spp. were obtained on three different solid media. The results obtained on Antibiotic...
Journal Articles
Chemotherapy (1979) 25 (5): 286–295.
Published Online: 08 September 2009
...Kjetil Melby; Tore Midtvedt; Olle Dahl 6,042 strains of Staphylococcus aureus , Streptococcusfaecalis , Proteus mira-bilis , Escherichia coli , Kiebsiella sp . and Pseudomonas sp . were tested against tobramycin and gentamicin. Among all species studies, except Pseudomonas sp , gentamicin turned...
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Chemotherapy (1984) 30 (2): 84–87.
Published Online: 08 September 2009
...Milap C. Nahata; Dwight A. Powell; Diane Durrell; John P. Glazer The delivery of tobramycin was studied at the flow rates of 2, 4 and 6 ml/h after injection into the various sites of IVAC, IMED and Auto Syringe infusion systems. The actual times were markedly longer than the predicted times...
Journal Articles