...M. Ogawa; S. Goto; F. Ishikawa; I. Kimura The inhibitory effect of various β -lactams on antibody production in the spleen was evaluated in mice immunized with sheep red blood cells by Cunningham’s method. With a few exceptions, cephem derivatives were more effective than the penicillins tested...

... on erythropoiesis in the spleen of nonirradiated animals, and clearly proved this in irradiated ones. Depression in the bone marrow of nonirradiated animals was not observed, in irradiated animals a depressive effect was shown, though less strong than in the spleen. As befits these findings there is an accentuation...