... of influenza. Methods: An in-house compound library was screened using a cytopathic effect inhibition assay. Selected hits were then tested in vivo and used as a core skeleton for derivative synthesis. Results: The hit compound (BMD-2601505) was effective [50% effective concentration (EC 50 ) of 60-70 μ M...

...Zrinka Bošnjak; Vanda Plecko; Ana Budimir; Ivana Mareković; Branka Bedenić Background: Acinetobacter spp. is an opportunistic pathogen that has demonstrated increasing relevance in nosocomial infections. Carbapenem-resistant strains have been reported worldwide. Methods: Since 2014, screening...

... exhibited antibiotic hypersusceptibility like the oprM -deficient cells, indicating that PlcH-OprM was translocated across the inner membrane exclusively through the Tat system. Conclusions: This system can be used for the screening of Tat system inhibitors and will be an excellent model for the study...

... to a vascular surgery ward during a 3-month period. Methods: MRSA screening was accomplished through the acquisition of nasal, throat and perineal swabs. These swabs were placed in tryptic soy broth that had been supplemented with 6.5% NaCl and incubated for 24 h. The resulting isolates were subcultured on agar...

...K. Dornbusch; B. Lindeberg; C.-E. Nord; Stig Thunell In group practice, screening for bacteriuria and antibacterial susceptibility testing of bacteria in urine specimens were performed by dipslide methods (Uricult® and Sensicult®, Orion Diagnostica) and the results were evaluated with respect...

... of Biology and Agriculture, Nuclear Research Institute, Tuwaitha, Baghdad Key Words. Leishmania Promastigotes Kala azar In vitro Screening Pentostam Flagyl Dehydroemetine Abstract. Sodium stibogluconate, metronidazole and dehydroemetine Roche were tested for their in vitro action...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Antibacterial susceptibility testing Dip-slide method Urine specimens Screening ...

... infection Rat Chemotherapeutic tests Viable counts Statistical evaluation Reproducibility Screening Different strains Chemotherapy 17: 293-304 (1972) Rapid Quantitative Evaluation of Chemotherapeutic Agents in Experimental Cystitis of Rats1 W. A. VlSCHER Biological Research Laboratories...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Echinococcus Scolices Screening 64 compounds Treatment Prophylaxis Toxicity Chemotherapy 16: 371-379 (1971) Systematic Search for a Systemic Hydatid Scolicide I. In vitro...

...R.J. Cenedella; L.H. Saxe; K. Van Dyke An automated (robot) wet-chemistry system has been developed and is being used routinely for mass screening of candidate compounds for antimalarial activity by measuring the ability of these compounds to inhibit glucose consumption and lactic acid production...