... infections, which are mainly caused by Gram-negative pathogens. For years, levofloxacin and other FQs have been the first-line drugs for treating National Institutes of Health (NIH) category II chronic bacteria prostatitis (CBP). Eradication rates achieved by levofloxacin in the frame of randomized trials...

...M. Dan; J. Golomb; A. Gorea; A. Lindner; S.A. Berger Concommitant concentrations of norfloxacin in serum, urine and prostatic tissue were determined in 12 patients following a single oral dose of 400 mg. Tissue levels ranged from 0.3 to 1.73 mg/kg, and therapeutic concentrations were demonstrable...

...J.M. Symes; J.D. Jarvis; G.C. Tresidder Studies were carried out on a series of patients with chronic bacterial prostatitis and on a series of patients who had undergone vasectomy or prostatectomy, to determine whether cephalexin monohydrate could be found at a bacteriocidal level in semen...

...Konstantin Charalabopoulos; George Karachalios; Dimitrios Baltogiannis; Alexander Charalabopoulos; Xenofon Giannakopoulos; Nikolaos Sofikitis In the present review article, the penetration of antimicrobial agents into prostatic fluid and tissue was examined. Three major factors determining...