... infections, which are mainly caused by Gram-negative pathogens. For years, levofloxacin and other FQs have been the first-line drugs for treating National Institutes of Health (NIH) category II chronic bacteria prostatitis (CBP). Eradication rates achieved by levofloxacin in the frame of randomized trials...

...M. Whitby; J. Hempenstall; C. Gilpin; L. Weir; G. Nimmo Concomitant concentrations of monobactam antibiotics were measured in plasma and in prostatic tissue obtained by transurethral resection in 25 patients, 60–120 min after dosage. A 1-gram single intravenous injection of aztreonam or carumonam...

...J.B.J. Boerema; A. Dalhoff; F.M.Y. Debruyne The penetration of ciprofloxacin into prostatic tissue was studied following oral administration of 500 mg either once or repeatedly in 12-hourly intervals. Following single administration ciprofloxacin was rapidly absorbed from the gastrointestinal tract...

...D. Melloni; P. Ammatuna; P. Formica; V. Falletta; F. Gaglio; M. Cacciatore; G. Messina Cephalosporins do not reach active therapeutical concentrations in the prostatic tissue in patients suffering from chronic bacterial prostatitis. Cefoperazone is an exception. Its efficacy in the treatment...

...T.A. Plomp; K.M. Schalkhäuser; R.A.A. Maes The concentration of thiamphenicol in prostatic tissue, testicular tissue and serum after a single intravenous injection of 1 g thiamphenicol glycinate ester was investigated. The prostatic and testicular specimens were obtained by prostatectomy...

...Konstantin Charalabopoulos; George Karachalios; Dimitrios Baltogiannis; Alexander Charalabopoulos; Xenofon Giannakopoulos; Nikolaos Sofikitis In the present review article, the penetration of antimicrobial agents into prostatic fluid and tissue was examined. Three major factors determining...