... the effect of a choline dendrimer with maximized binding affinity/specificity for CBPs on microglia-mediated pneumococcal phagocytosis. Methods: Pneumoccocal cultures were exposed to dendrimers containing 8 choline end groups or amino groups as controls, either from the beginning of bacterial growth...

... the adequate therapy of infections caused by Gram-negative bacteria. We tested our hypothesis that linezolid impairs phagocytosis and the killing of Gram-negative bacteria by polymorphonuclear leukocytes (PMN). Methods: The influence of clinically relevant concentrations (5, 20 and 50 mg/l) of linezolid...

... for phagocytosis and oxidative burst capacity with Staphylococcus aureus opsonized with pooled human serum as stimuli. Flow cytometric techniques were used to compare PMN phagocytosis and oxidative burst with and without incubation in different concentrations of the drugs. Results: None of the drugs influenced PMN...

... Staphylococcus aureus Peptidoglycan Phagocytosis Immune sera, rabbit SDS-PAGE electrophoresis Teichoic acid Ultrasound cell lysates Antigens, whole cell Chemotherapy Experimental Chemotherapy Chemotherapy 1996;42:118-132 Walter H. Traub Dierk Bauer Birgit Leonhard Institut fur Medizinische...

... phagocytosis was unaffected by RKM, while luminol-amplified chemiluminescence (LACL) was significantly reduced by 50 and 100 μg/ml. When PMNs were washed after incubation phagocytosis was not modified but LACL was significantly restored. These characteristics of RKM were similar to those of roxithromycin...

...Pérez Fernández; I. Herrera; P. Martínez; M.L. Gómez-Lus; J. Prieto Phagocytosis and intracellular killing of invading pathogens by host cells play the major role in resistance to bacterial infections. In vitro, antibiotics improve the susceptibility of microorganisms to antimicrobial activity...

... exposure of bacteria to high levels of antimicrobials can affect their interaction with leukocytes. The susceptibility of Escherichia coli to phagocytosis and killing by human polymorphonuclear leukocytes in the presence of normal human serum following treatment with RP7293, a new natural streptogramin...

...P.C. Braga; G. Piatti; Dal Sasso; S. Maci; E. Blasi The in vitro effects of ceftibuten on human polymorphonuclear leukocyte (PMN) chemotaxis, phagocytosis and chemiluminescence were investigated. PMN from healthy adult donors were incubated for 1 h in medium alone or in medium containing increasing...

... to these aspects, the influence of brodimoprim (BMP), a dimethoxybenzylpyrimidine recently entered into clinical use, on human PMN phagocytosis and oxidant radical production (chemiluminescence) was investigated. PMNs from healthy adult donors were incubated for 50 min in medium alone or in medium containing...

...Isabel García; Alvaro Pascual; Sofía Ballesta; Evelio J. Perea The effect of phagocytosis of Escherichia coli , Staphylococcus aureus and Haemophilus influenzae on the intracellular penetration of sparfloxacin into human polymorphonuclear neutrophils (PMN) was evaluated. The intracellular...

...F. Fraschini; F. Scaglione; F. Ferrara; S. Dugnani; M. Falchi; G. Cattaneo The effects of miokamycin on the immune system were studied in healthy volunteers by means of the following assays: phagocytosis, intracellular killing and natural killer activity. The tests were performed before, 2 and 6 h...

..., instructions or products referred to in the content or advertisements. Clindamycin Klebsiella pneumoniae sepsis Phagocytosis Microbiology Chemotherapy 90:36:337-344 © I990S. Karger AG, Basel 0009- 3 157/90/0365-0337 $ 2.75/0 In vitro and in vivo Effects of Subinhibitory Concentrations...

.... Ciprofloxacin Ofloxacin Phagocytosis Intracellular activity Chemotherapy 1989;35:17-22 © 1989 S. Karuer AG. Basel 0 0 0 9 -3 157/89/0351-0017$ 2.75/0 Effect of Ciprofloxacin and Ofloxacin on Human Polymorphonuclear Leukocyte Activity against Staphylococci A. Pascual, L. Martinez-Martinez, E.J. Perea...

.... For the ex vivo study, 7 adult healthy controls were treated intravenously with 4 g/day of cefodizime for 6 days. We found that the drug modulated phagocytosis frequency and index when nonopsonized zymosan and heat-killed Candida albicans were used as phagocytic challenge both in vitro (from 25 μg/ml) and ex...

...F. Fraschini; F. Scaglione; F. Ferrara; O. Marelli; P.C. Braga; F. Teodori The effects of erythromycin on the immune system have been studied in healthy volunteers and patients suffering from chronic bronchopneumonial diseases, by means of the following assays: phagocytosis, natural killer activity...

... of IgG (Fcy-R) and C3b (C3b-R). Random migration in capillary tubes was significantly decreased, but phagocytosis as measured by chemiluminescence was only slightly decreased. The proportion of lymphocytes bearing Fcy-R was decreased, while there was no effect on lymphocyte C3b-R percentage, nor...

...F. Fraschini; F. Scaglione; F. Ferrara; S. Dugnani; L. Zecca The effects of lincomycin on the immune system were studied on patients suffering from chronic bronchitis by means of phagocytosis, chemotaxis and natural-killer tests. The tests were performed before and 2, 4, 8, 12 and 24 h after...

...L. Athlin; L. Domellöf The effects of fluorouracil and adriamycin as single drugs and in combination with mitomycin (FAM) on the phagocytosis of tissue macrophages were studied in vitro. Human peritoneal macrophages (HPM) from cancer patients or uremic patients on peritoneal dialysis were incubated...

... blood Fosfomycin Group A (phage tail) bacteriocins Intraphagolysosomal bactericidal activity Mezlocillin Phagocytosis Phenylbutazone Piperacillin Rifampin Serratia marcescens Abstract. Neither cefoperazone, cefotaxime, mezlocillin nor piperacillin significantly killed intraphagocytic...

... to Enhance Combined Phagocytic and Serum Bactericidal Activity of Normal Blood against Serratia marcescens Walter H. Traub Institut für Hygiene und Mikrobiologie, Universität des Saarlandes, Homburg/Saar, FRG Key Words. IgG immunoglobulin 'Natural' IgG antibodies Phagocytosis Serum bactericidal activity...