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Keywords: Norfloxacin
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Journal Articles
Chemotherapy (2017) 62 (3): 194–198.
Published Online: 24 March 2017
...-negative bacteria compared with other quinolones. Conclusion: Compounds obtained by modifications on C-7 of norfloxacin with the acetylated piperazinyl, halogen atoms, and substituted hydrazinyl showed good in vitro activity - some even better than the original compound. jaimecardoso@uaz.edu.mx...
Journal Articles
Chemotherapy (1995) 41 (2): 92–99.
Published Online: 11 September 2009
... culture. By limiting the nutrient supply, generation times were lengthened from approximately 0.45 to 1.5 h up to 3.9 h. Three recent clinical isolates each of Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa were exposed to twice the MIC of ciprofloxacin, norfloxacin, fleroxacin...
Journal Articles
Chemotherapy (1993) 39 (6): 394–399.
Published Online: 11 September 2009
... rate and drug concentration was established. Sparfloxacin and temafloxacin were the most active quinolones assayed with greater lethal rates than ciprofloxacin and norfloxacin. The relation was biphasic with a decrease of at least 1 log 10 c.f.u./ml at high drug concentrations with respect...
Journal Articles
Chemotherapy (1994) 40 (6): 369–373.
Published Online: 11 September 2009
...Alan H. Lau; Ignatius Tang; John Fitzloff; Rashmi Jain The effect of hemodialysis on norfloxacin removal was evaluated in 7 patients. Single 800-mg doses of the drug were given to the subjects prior to dialysis using cuprophan hollow fiber dialyzers. Arterial and venous sample pairs were obtained...
Journal Articles
Chemotherapy (1993) 39 (1): 36–39.
Published Online: 11 September 2009
...S.C. Lafredo; B.D. Foleno; K.P. Fu Twelve strains of Streptococcus pneumoniae were serially exposed to increasing concentrations of levofloxacin, temafloxacin, ciprofloxacin and norfloxacin for five passages. Wild-type and passaged strains were tested for susceptibility to quinolones, macrolide...
Journal Articles
Chemotherapy (1991) 37 (1): 6–14.
Published Online: 10 September 2009
...Haragopal Thadepalli; See Kean Chuah; Carmen D. Thadepalli; Ashis K. Mandal The antimicrobial activity of intravenously given quinolones on the intestinal microflora was unknown and therefore studied in dogs with a surgically isolated loop of the jejunum. Ciprofloxacin, enoxacin and norfloxacin...
Journal Articles
Chemotherapy (1985) 31 (2): 112–118.
Published Online: 09 September 2009
...D.L. Shungu; V.K. Tutlane; E. Weinberg; H.H. Gadebusch 302 clinical isolates representing 16 bacterial species most often implicated in ocular infections were tested in vitro against norfloxacin and a panel of antibacterial agents. On the basis of the 90% minimal inhibitory concentration (MIC 90...
Journal Articles
Chemotherapy (1985) 31 (1): 19–28.
Published Online: 09 September 2009
...W. Cullmann; M. Stieglitz; B. Baars; W. Opferkuch The antibacterial activity of the new quinolone compounds enoxacin, norfloxacin, ofloxacin and ciprofloxacin was evaluated in 300 Enterobacteriaceae , 50 Pseu-domonas aeruginosa , 30 Acinetobacter spp., 15 Haemophilus influenzae , 50 Streptococcus...
Journal Articles
Journal Articles
Chemotherapy (1988) 34 (2): 117–126.
Published Online: 09 September 2009
...W. Kern; H. Gulden; E. Vanek; E. Kurrle The antibacterial activity of imipenem combined with norfloxacin, ciprofloxacin, or ofloxacin against 43 gram-positive cocci and 53 aerobic gram-negative rods isolated from hospitalized patients was determined by the checkerboard method and compared...
Journal Articles
Journal Articles
Chemotherapy (1987) 33 (5): 355–360.
Published Online: 09 September 2009
...M. Castelli; M.L. Barbieri; A. Bertolini; R. Bossa; I. Galatulas Norfloxacin and adriamycin were tested alone and in combination for bactericidal activity against different strains of gram-negative bacteria. The antitumoral effect of a combination of norfloxacin and adriamycin was determined...
Journal Articles
Chemotherapy (1990) 36 (5): 345–355.
Published Online: 09 September 2009
... 90 ) of the compound against gram-positive aerobic bacteria was higher or comparable to those of ciprofloxacin, ofloxacin, and norfloxacin. Against most gram-negative enteric bacteria and Pseudomonas species, temafloxacin was less active than ciprofloxacin, but was generally as active as ofloxacin...
Journal Articles
Chemotherapy (1990) 36 (6): 403–406.
Published Online: 09 September 2009
...P. Hohl; A.M. Felber Fleroxacin (Ro 23-6240, AM-833), a new fluoro-4-quinolone, was tested in vitro against 273 gram-positive clinical isolates. Norfloxacin, a quinolone mostly used in urinary tract infections, was included as a standard. Overall, in vitro activities of fleroxacin and norfloxacin...
Journal Articles
Chemotherapy (1987) 33 (4): 240–242.
Published Online: 09 September 2009
...M. Dan; J. Golomb; A. Gorea; A. Lindner; S.A. Berger Concommitant concentrations of norfloxacin in serum, urine and prostatic tissue were determined in 12 patients following a single oral dose of 400 mg. Tissue levels ranged from 0.3 to 1.73 mg/kg, and therapeutic concentrations were demonstrable...
Journal Articles
Chemotherapy (1986) 32 (3): 291–298.
Published Online: 09 September 2009
...T. Fujimoto; M. Sato; K. Katami; Y. Osada; M. Tsumura; H. Tachizawa; T. Une Ofloxacin, a new pyridone-carboxylic acid derivative, was evaluated in descending nephritis and subcutaneous abscess models with Staphylococcus aureus in mice in comparison with norfloxacin. Descending nephritis...
Journal Articles
Chemotherapy (1990) 36 (Suppl. 1): 46–49.
Published Online: 09 September 2009
... was compared to a 7-day treatment with norfloxacin 400 mg b.i.d. Midstream urocultures and susceptibility tests were performed to diagnose a UTI and at 3–5 and 25–35 days after discontinuation of therapies. Our results, showing comparable clinical and bacteriological resolution rates in both groups (76.6...
Journal Articles
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Journal Articles
Chemotherapy (1985) 31 (5): 372–382.
Published Online: 09 September 2009
...Walter H. Traub Five multiple-drug-resistant (MDR) Corynebacterium isolates , which differed in several biochemical traits, were sensitive to rifampin, vancomycin and ciprofloxacin; ciprofloxacin was more active than enoxacin and norfloxacin. The MDR Corynebacterium isolates uniformly were...