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Keywords: Meningitis
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Journal Articles
Journal Articles
Chemotherapy (1997) 43 (4): 264–271.
Published Online: 11 September 2009
...H. Schmidt; G. Zysk; R.R. Reinert; W. Brück; A. Stringaris; V. Chen; K. Stuertz; F. Fischer; R. Bartels; K.-J. Schaper; S. Weinig; R. Nau Rifabutin is a lipophilic antibacterial with high in vitro activity against many pathogens involved in bacterial meningitis including pneumococci. Resistance...
Journal Articles
Chemotherapy (1991) 37 (Suppl. 3): 3–6.
Published Online: 10 September 2009
... responsive to ceftriaxone therapy. The mean period of outpatient treatment in initially hospitalized children with non-CNS infections, excluding endocarditis, was 1–3 days. Ceftriaxone outpatient management was successful in the control of organisms causing meningitis (n = 54), periorbital facial cellulitis...
Journal Articles
Journal Articles
Chemotherapy (1989) 35 (Suppl. 1): 101–105.
Published Online: 09 September 2009
...A. Constantopoulos; L. Thomaidou; H. Loupa; G. Papoulias Aztreonam was administered to 25 neonates (16 term, 9 premature) with clinically and bacteriologically proved gram-negative infections. Ten patients had meningitis, 9 had septicemia and 6 had urinary tract infections. Patients were between 1...
Journal Articles
Chemotherapy (1990) 36 (2): 109–116.
Published Online: 09 September 2009
...-9424 against K. pneumoniae . In a murine meningitis infection caused by S. pneumoniae , Ro 23-9424 was 3 times as active as cefotaxime, while fleroxacin was inactive. When meningitis was induced by K. pneumoniae , Ro 23-9424 was as active as the quinolone, while cefotaxime was inactive...
Journal Articles
Chemotherapy (1985) 31 (4): 304–309.
Published Online: 09 September 2009
... bacteremia and meningitis revealed that imipenem was highly effective. This was shown by (1) rapid bacterial clearance from the blood and cerebrospinal fluid; (2) rapid sterilization of the blood and cerebrospinal fluid; (3) prevention of the development of meningitis in bacteremic animals, and (4) reduction...
Journal Articles
Chemotherapy (1986) 32 (2): 89–94.
Published Online: 09 September 2009
...Milap C. Nahata; Diane E. Durrell; William J. Barson 20 patients (0.4–5.6 years old) receiving ceftriaxone for the treatment of bacterial meningitis were studied. Simultaneous serum and cerebrospinal fluid concentrations of ceftriaxone were determined by HPLC in 15 patients at 11.4–12.8 h after...
Journal Articles
Chemotherapy (1987) 33 (3): 177–182.
Published Online: 09 September 2009
... were 2- to 4-fold greater than those of penicillin G. In vivo studies were carried out with an experimental bacteremia and meningitis model in newborn rats. Eighty-one infected animals were randomized to receive teicoplanin 5, 10 or 20 mg/kg, twice daily, or penicillin G 50 or 200 mg/kg, twice daily...
Journal Articles
Chemotherapy (1988) 34 (Suppl. 1): 47–52.
Published Online: 09 September 2009
...Isidro Zavala; Enrique Barrera; Arnulfo Nava Twenty-six adults with acute bacterial meningitis were enrolled in an open randomized comparative study. The organisms isolated from CSF were Streptococcus pneumoniae , Staphylococcus epidermidis , Haemophilus influenzae , Escherichia coli and Salmonella...
Journal Articles
Journal Articles
Chemotherapy (1982) 28 (4): 304–309.
Published Online: 08 September 2009
...A. Alejo; J. Aznar; J. Romero; M.C. García-Iglesias; M. Losana; E.J. Perea We have studied the clinical efficacy and pharmacokinetics of cefuroxime in 3 children aged 5, 7 and 10 months who were suffering from meningitis due to Haemophilus influenzae group b ( β -lactamase producers). The MICs...
Journal Articles
Journal Articles
Chemotherapy (1980) 26 (3): 196–206.
Published Online: 08 September 2009
...Y.H. Tsai; R.S. Hirth; F. Leitner Meningitis and meningoencephalomyelitis caused by Listeria monocytogenes were experimentally established in mice. The pathological changes in brain and spinal cord resulting from the infection resemble those observed in man and domestic animals. The efficacy of 24...
Journal Articles
Chemotherapy (1981) 27 (5): 303–308.
Published Online: 08 September 2009
...O. Brückner; M. Alexander; H. Collmann Concentrations of tobramycin in cerebrospinal fluid (CSF) and serum of neurosurgical and of meningitis patients were determined following systemic application of 80-mg doses. Tobramycin was detectable only in 8 tests out of 17 in CSF of 11 neurosurgical...
Journal Articles
Chemotherapy (1983) 29 (4): 237–243.
Published Online: 08 September 2009
... was consistently faster in tests performed by HPLC than those using microbioassay. The clinical efficacy in gram-negative bacillary meningitis is to be explained by levels of the parent compound CTX in CSF which are several times higher than the minimal inhibitory concentrations (MICs) of most enterobacteriaceae...
Journal Articles
Chemotherapy (1983) 29 (6): 428–435.
Published Online: 08 September 2009
... and meningitis revealed that TMP/SMZ penetrated well into the cerebrospinal fluid (CSF) and that 37% of serum levels were achieved. The efficacy of TMP/SMZ was compared with that of ampicillin, chloramphenicol, cefotaxime and lamoxactam. Bacterial clearance from blood and CSF was significantly greater with TMP...
Journal Articles
Chemotherapy (1977) 23 (Suppl. 1): 189–195.
Published Online: 05 August 2009
...J. Llorens; A. Lobato; T. Olay This report deals with the results of a study that was made on the passage of fosfomycin into the CSF in 22 children with meningitis (11 parotideal meningitis and 11 meningococcal meningitis). The plasma and liquor levels of fosfomycin were determined in the acute...
Journal Articles
Chemotherapy (1977) 23 (Suppl. 1): 180–188.
Published Online: 05 August 2009
...L. Drobnic; M. Quiles; A. Rodríguez In order to determine the liquor concentration of fosfomycin, we chose 27 patients who were suffering from meningitis with different etiology. According to route, type of administration and doses employed, we classified the patients into five groups. Blood...
Journal Articles