...Markus Ruhnke; Matthias Trautmann; Klaus Borner; Walter Hopfenmüller The pharmacokinetics of ciprofloxacin were evaluated in 11 patients (3 patients with impaired renal function) with advanced liver cirrhosis after a single oral dose of 500 mg. Mean serum peaks were 2.80 ± 1.00 mg/l in 64 ± 37 min...

...P.A. Miglioli; P. Pivetta; R. Orlando; P. Palatini; A. Varotto; L. Okolicsanyi The pharmacokinetics of miocamycin, a new macrolide antibiotic, was studied in 6 healthy controls and 6 patients with compensated liver cirrhosis. The results indicate that in chronic liver disease the kinetics...