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Keywords: Leukemia
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Journal Articles
Chemotherapy (2023) 68 (2): 115–118.
Published Online: 06 June 2023
... indications for azacitidine use in the adverse event reports were myelodysplastic syndrome (48%) and acute myelogenous leukemia (27%). Physicians reported 44% of the azacitidine-induced pericarditis reports, while other health professional reported 52% of the reports. The disproportionality analysis showed...
Journal Articles
Chemotherapy (2019) 63 (6): 308–314.
Published Online: 06 March 2019
... resistance HL-60 cells Idarubicin Leukemia - TEL-MN1 fusion First of all, in order to investigate the effect of TEL-MN1 fusion expression on cell proliferation and drug resistance, the HL-60 cell model with overexpressed TEL-MN1 fusion was constructed. qRT-PCR was applied to confirm...
Journal Articles
Journal Articles
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Journal Articles
Chemotherapy (1987) 33 (2): 110–122.
Published Online: 09 September 2009
.... DFMO-induced cellular polyamine depletion does enhance MGBG uptake into HL60 cells, but treatment with high concentrations of DFMO, which deplete polyamines to the extent that growth is inhibited, negate this effect. Difluoromethylornithine Methylglyoxal-bis(guanylhydrazone) Leukemia HL60 cells...
Journal Articles
Journal Articles
Chemotherapy (1971) 16 (2): 76–84.
Published Online: 19 May 2009
..., and a comparison was made between the ability of the drugs to inhibit this incorporation into leukocytes of normal blood and of various types of leukemia. Three drugs, quinacrine, cytosine arabinoside and 6-mercapto-purine were tested in this system in concentrations ranging from 10 -8 –10 -4 m. 19 5 2009...
Journal Articles
Chemotherapy (1972) 17 (4): 283–292.
Published Online: 19 May 2009
...L.C. Mishra; J.A.R. Mead The antitumor activity of dihydrohomofolate against L1210 and L1210/FR-8 leukemia was studied and found to be comparable to that of tetrahydrohomofolate. Pretreatment of mice with methotrexate. a potent inhibitor of dihydrofolate reductase, decreased the antitumor activity...
Journal Articles
Chemotherapy (1970) 15 (2): 105–110.
Published Online: 18 May 2009
... of Chlorprothixene. Chlorprothixene failed to enhance the anti-L1210 activity of the fluorinated pyrimidine analogues, 5-FU and Fluoxidine. Chemotherapy 15: 105-110 (1970) Combination Chemotherapy of Mouse Leukemia L 1210 with a Neuroleptic and Antimetabolites V. Pujman1, J. Sandberg, L. H owsden and A. G oldin...
Journal Articles
Journal Articles
Chemotherapy (2008) 54 (3): 157–165.
Published Online: 18 June 2008
... of sanguinarine on the induction of apoptosis using U937 leukemia cells. Methods: Cytotoxicity was evaluated by MTT assay. Apoptosis was detected using DAPI staining, agarose gel electrophoresis and flow cytometry. The protein levels were determined by Western blot analysis. Casapse-3 activity was measured using...
Journal Articles
Journal Articles
Chemotherapy (2004) 50 (5): 221–228.
Published Online: 22 November 2004
...M.G. Ramos; F.L.A. Rabelo; G. Brumatti; A.E. Bueno-da-Silva; G.P. Amarante-Mendes; J.I. Alvarez-Leite Background: Apoptosis is an essential form of cell death, the failure of which can lead to cancer development. Cancer including leukemia is usually treated with chemotherapeutic drugs that can...