..., and several cases of reactivation of latent infections by opportunistic agents in patients in treatment with ruxolitinib have been published in the last years. Several pathophysiological mechanisms may explain an association between ruxolitinib and opportunistic infections. From what we know, the only case...

...Patrick J. Van Reempts; Bart Van Overmeire; Ludo M. Mahieu; Karel J. Vanacker The safety of ceftriaxone has been evaluated in 80 neonates who were treated empirically for suspected infection with either ceftriaxone and ampicillin (group A, age 0-72 h) or ceftriaxone and vancomycin (group B, age...

...J.A. McGregor; F.B. Christensen; J.I. French We evaluated the efficacy, patient and medical staff acceptance, and costs of intramuscular therapy with imipenem/cilastatin for mild to moderate upper reproductive tract infection in hospitalized women in an open study. Thirty-five patients were...

.... Antimicrobial Protein binding Cephalosporin Infection Staphylococcus aureus Abstract. Protein binding, serum kinetics and minimum inhibitory concentrations (MICs) for Staphylococcus aureus were determined for cefoxitin, cefazolin, ceftazidime and cetriaxone in the rabbit. MICs of cefazolin and cefoxitin...

...Tadami Nagao; Mitsumoto Komatsuda; Kunihiko Yamauchi; Hiroyuki Nozaki 27 episodes of infection in patients with acute leukemia were treated with combination of cefmetazole and piperacillin. Causative bacteria were isolated in each infection. The patients were treated with 6 g cefmetazole and 15 g...

...A.K. Miller; Y.L. Kong; E.O. Stapley Haemophilus influenzae is an important pathogen in respiratory infections in children and often is implicated in otitis media. It is sensitive in vitro to a number of antibiotics, some of which are used clinically for the treatment of such infections. We have...

...W.W. Eudy; S.E. Burrous Generation times of Proteus mirabilis and Escherichia coli in experimental kidney infections have been determined using radio-isotope techniques. During the first 7 hours following infection, generation times of 2.3 and 0.9 h were determined for P. mirabilis and E. coli...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Gentamicin, adverse effects Infant, newborn Infection Chemotherapy 18: 141-153 (1973) A Follow-Up Study on the Cochlear, Vestibular and Renal Function in Children Treated with Gentamicin...

...L. Degen; M. Salvaterra; S. Vella; M. Pesatori The in vivo activity of Rec 15-0122 (nifurpipone), a new water-soluble nitrofuran derivative, has been investigated in some standardized infections. The drug, after oral administration, is active in mice in systemic infections with Streptococcus...

... be prolonged by treatment Mice with emetine dihydrochloride. Optimal dosage Leukemia L1210 schedules required emetine administration daily for Infection 5 days (QD, day 1-5) or intermittently on every Entameba histolytica 4th day. (Q4D, day 1, 5, 9). Compounds related to Lifespan emetine which are active...

...L. Biró; Éva Iván With model experiments we endeavoured to further clinical experience in that infection of patients in a state of immunodepression may be treated more efficiently with bactericidal than with bacteriostatic antibiotic drugs. In cases of lethal infection due to Staphylococcus aureus...

...E. Grunberg; W.F. DeLorenzo; E. Titsworth A procedure is described by which the effectiveness of a chemotherapeutic agent such as sulfamethoxazole (5-methyl-3-sulfanilamido-isoxazole) in the treatment of established bacterial infections in mice can be demonstrated visually. © 1970 S. Karger AG...

...Reuben Ramphal Background: It has become an article of faith that appropriate antibiotic therapy is needed for best outcomes during a serious infection. Despite this long-held view, there is some debate about the role of appropriate outcome in serious infections, in particular with nosocomial...

...G. Karachalios; G. Bablekos; I. Karachaliou; L. Zoganas; A. Charalabopoulos; K. Charalabopoulos Cardiac myxomas are rare tumors which may present differently. Left atrial myxoma is an entity from anatomopathological and clinical aspects. To the best of our knowledge, only 2 cases of infected left...

.... The end point was the occurrence of infections within 10 days. The costs of antibiotic treatment were also calculated. Results: 96% of the ceftriaxone patients (n = 97) and 95% of the cefoxitin group (n = 98) remained infection-free. In neither treatment group was deep infection, abscess, phlegmon...

..., with no further doses. The groups were similar with respect to age, operative procedure, operative time and time to discharge after operation. The patients who received ceftriaxone prophylaxis had 54.4% fewer overall infections than those who received ceftazidime prophylaxis. Wound infection occurred in 0.45...