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Keywords: Herpes simplex
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Journal Articles
Chemotherapy (1993) 39 (3): 203–211.
Published Online: 11 September 2009
... of type 2 herpes simplex virus. The 50% effective concentrations (EC 50 s) were 1-2 μ M . Acyclovir, which was run in parallel, had values of 4-28 μ M . Surprisingly, the compound was inactive against human cytomegalovirus. SP-303 was also virucidal at 50 μM. Interferon was not induced. The mode...
Journal Articles
Journal Articles
Chemotherapy (1981) 27 (3): 209–213.
Published Online: 08 September 2009
...Richard S. Griffith; Donald C. DeLong; Janet D. Nelson In the studies conducted, arginine deficiency suppressed herpes simplex virus replication in tissue culture. Lysine, an analog of arginine, as an antimetabolite, antagonized the viral growth-promoting action of arginine. The in vitro data may...
Journal Articles
Journal Articles