... derepressed cephalosporinase-producing Enterobacter cloacae strain in immunocompetent and leucopenic rats. Methods: Sixty Wistar rats were used. Leucopenia was induced in half of them by a single intravenous administration of 30 mg/kg cyclophosphamide, while the remaining rats received the same volume...

...Mohammed A. Ramadan; A.F. Tawfik; A.M. Shibl During surveillance studies, a total of 66 strains of gram-negative bacilli (28 Enterobacter cloacae, 20 Serratia marcescens and 18 Pseudomonas aeruginosa ) with a reduced susceptibility to third-generation cephalosporins, aztreonam and amikacin were...

...-inducing antibiotics, cefoxitin and imipenem, was measured. The Enterobacter cloacae (n = 35) population was strikingly bimodal, expressing ‘all-or-none’ cross-resistance to β-lactams (except imipenem) corresponding to the baseline level of β-lactamase expression. E. aerogenes (n = 14) displayed a less...

...L.S. Tzouvelekis; A.F. Mentis; E. Tzelepi; A. Tsakris; K. Kyriakis; N.J. Legakis The effects of netilmicin exposure on two aminoglycoside (AMG)-resistant and two AMG-susceptible Enterobacter cloacae isolates were studied. It was found that 1 h incubation of bacterial suspensions with netilmicin...

...J. Stoorvogel; M.H. Van Gestel; Ketelaar-van Gaalen; R.P. Mouton; J.A.M. van de Klundert Eight strains of Enterobacter cloacae with varying patterns of susceptibility to β-lactam antibiotics were studied to compare the inducibility and expression of their β-lactamase genes. These strains included...

...-resistant strain of Enterobacter cloacae (isolate No. 19) yielded most consistent results as compared with several other β -lactamase producers; the E. cloacaeβ -lactamase(s) was neutralized by clavulanic acid. Spot inocula of E. cloacae isolate No. 19, following overnight ‘induction’ with 1 μ g/ml...

...Walter H. Traub; Marlene Spohr The combinations of 11 antimicrobial drugs and fresh human defibrinated blood were examined for potential additive effects against several isolates of Enterobacter cloacae recovered from patients with bacteremia or meningitis. Aminoglycosides (amikacin, gentamicin...

...Walter H. Traub; Rolf Hüberle; Dierk Bauer Two multiple drug resistant Enterobacter cloacae isolates (Nos. 460 and 493) varied phenotypically in bacteriocin susceptibility in the absence of significant·antigen variation. Both isolates were susceptible to chloramphenicol, nitrofurantoin, polymyxin B...

...Howard S. Carr; Herbert S. Rosenkranz A strain of Enterobacter cloacae resistant to silver sulfadiazine was recovered from a unit in which this antimicrobial agent was in use. This strain was found to harbor an R factor responsible for resistance to carbenicillin, kanamycin and ampicillin...

...Joe E. Coward; Herbert S. Rosenkranz Upon exposure of Enterobacter cloacae to silver sulfadiazine, a number of ultrastructural changes involving the cell envelope take place. Foremost among these is a modification of the cell wall from an undulating structure to one which is smooth and has become...