... failure after treatment with different antibiotics (amoxicillin, ciprofloxacin, cefazolin, clindamycin) and acetaminophen, or a combination of these drugs. Moreover, we provide an overview of the hepatotoxic potential of these drugs. [email protected] 22 05 2017 12 08 2017 22 9 2017...

... are present. Objective: This study aimed to investigate the effect of ambroxol combined with ciprofloxacin on P. aeruginosa biofilm in a rat model. Methods: A rat model of acute lung infection was created by endotracheal (ET) intubation with a tube covered with a P. aeruginosa biofilm. The rats were treated...

...Sibel Dosler; A. Alev Gerceker Background: We investigated the in vitro activities of nisin alone or in combination with vancomycin and ciprofloxacin against methicillin-resistant (MRSA) and -susceptible Staphylococcus aureus (MSSA) strains. Methods: The minimum inhibitory concentrations were...

... culture. By limiting the nutrient supply, generation times were lengthened from approximately 0.45 to 1.5 h up to 3.9 h. Three recent clinical isolates each of Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa were exposed to twice the MIC of ciprofloxacin, norfloxacin, fleroxacin...

... or ceftriaxone plus netilmicin received additionally to the previous combination either vancomycin alone or combined with another anti-gram-negative compound: imipenem in those treated prophylactically with ofloxacin and ciprofloxacin in those without prophylaxis. The addition of vancomycin to the previously...

...T.H. Chan; S.S. Ho; C.K.W. Lai; S.W. Cheung; R.C.Y. Chan; A.F.B. Cheng; C.H.S. Chan A randomised double-blind controlled clinical trial was conducted to compare oral ciprofloxacin (500 mg b.d.) and amoxycillin (1 g t.d.s.) in the treatment of infective exacerbations of bronchiectasis. The commonest...

...Michael Whitby; Lesley Angus; Graeme Nimmo; Vernon Hill The efficacy and safety of fleroxacin and ciprofloxacin were evaluated in a single-centre, prospective, randomised, blinded study of patients with complicated urinary infection in a spinal injury unit. Patients were randomised to receive oral...

...Jasmina Vranes The effect of subinhibitory concentrations (sub-MICs) of ceftazidime, ciprofloxacin, and azithromycin on the hemagglutination (HA) and adherence ability of 29 P-fimbriated Escherichia coli strains to the buffalo green monkey kidney (BGMK) cell line was investigated. Comparisons were...

... organisms, while ciprofloxacin was only superior for the Pseudomonas spp. The percentage of isolates susceptible to ofloxacin was as follows: for respiratory tract pathogens = 94%, for skin and soft tissue infections = 94%, for urinary tract organisms = 93% and for genital tract isolates = 94%. © 1995 S...

... of fosfomycin were compared with ciprofloxacin, cefotaxime and pristinamycin. Pretreatment of S. aureus for 10 min with 4 × MIC of fosfomycin and ciprofloxacin clearly sensitized the bacteria to leukocytic killing in the presence of normal human serum (10% v/v); cefotaxime and pristinamycin failed to enhance...

...S.C. Lafredo; B.D. Foleno; K.P. Fu Twelve strains of Streptococcus pneumoniae were serially exposed to increasing concentrations of levofloxacin, temafloxacin, ciprofloxacin and norfloxacin for five passages. Wild-type and passaged strains were tested for susceptibility to quinolones, macrolide...

...B.M.A. Howard; R.J. Pinney; J.T. Smith A viable counting technique was used to determine the postantibiotic effect (PAE) of ciprofloxacin against four bacterial species, treated with either one or four times the minimum inhibitory concentration for 1 or 3 h. PAE were demonstrated with Escherichia...

... and ciprofloxacin, and imipenem caused globoid cell formations. These alterations were not uniform in every organism, but they correlated well with the duration of the PAE determined by viable counts. 11 9 2009 Microbiology Chemotherapy 1993;39:153-162 Magnus Gottfredssona Helga Erlendsddttir3 Ragnhildur...

...F. Legent; Ph. Bordure; C. Beauvillain; P. Berche A total of 251 adults with chronic sinusitis were enrolled into this prospective multicentre, double-blind, double-placebo comparison of ciprofloxacin (500 mg twice daily) with amoxy-cillin/clavulanic acid (500 mg three times daily). The diagnosis...

...A. Başaran; K. Erol; N. Başaran; H.V.V. Güneş; E. Açikalin; G. Timuralp; I. Değirmenci; E.A.A. Çakmak; A.G.G. Tomatir In the present study, ciprofloxacin, a fluoroquinolone antibiotic, was evaluated in vivo. The toxic effects of ciprofloxacin (20 and 200 mg/kg/day) on kidney and liver functions...

...F. Legent; Ph. Bordure; C. Beauvillain; P. Berche The efficacy and tolerability of ciprofloxacin (500 mg twice daily) was compared with that of amoxycillin/clavulanic acid (500 mg three times daily) in 76 patients with acute exacerbations of chronic non-cholesteatomatous suppurative otitis media...

... symptoms and inclusion in the study was 10.1 ± 12.1 years and the exacerbation had lasted 2.4 ± 4.4 months. Patients were given 500 mg ciprofloxacin twice daily for 9 days. Bacteriological specimens taken at inclusion were positive in 53.6% of cases, 25 Gram-positive and 16 Gram-negative pathogens being...

...L. Massias; P. Buffe; B. Cohen; Y. Cudennec; P. Gehanno; O. Sterkers; R. Farinotti This multicentre study evaluates the distribution of ciprofloxacin into the tissue structures of the middle ear following multiple dosing of one 500 mg tablet every 12 h. The samples were taken perioperatively from...

...P. Gehanno Malignant external otitis is a serious infection most frequently caused by Pseudomonas aeruginosa . Because of its antipseu-domonal activity and good tissue penetration, ciprofloxacin is an antibiotic which should, in theory, be effective in the treatment of this type of infection...

... of symptoms of otitis and enrolment in the study was 22.1 ± 19.4 years and the infective episode had been developing for 36.4 ± 72.4 days. The patients received either 500 or 750 mg ciprofloxacin twice daily for a period of 9 days with no topical antibiotic treatment. The bacteriological specimen taken...