.... Comparator drugs were ceftazidime and imipenem, i.e. antibiotics with known high and low endotoxin-liberating potential, respectively. As a parameter for biological responses to endotoxin, the release of proinflammatory cytokines (tumor necrosis factor-α, interleukin-1β) from monocytes/macrophages...

...F.J. Pérez; D. Navarro; C. Gimeno; J. García-de-Lomas Previously, it has been postulated that the porin OprC facilitates the diffusion of ceftazidime through the outer membrane of Pseudomonas aeruginosa. To further investigate this claim, the outer membrane protein (OMP) profiles of 22 ceftazidime...

... test. Time-killing curves were constructed for piperacillin, ceftazidime, cefepime and cefpirome against two susceptible and two resistant strains. The activities of cefepime and cefpirome against the resistant strains were impaired, and most of the strains were of intermediate sensitivity...

...Jasmina Vranes The effect of subinhibitory concentrations (sub-MICs) of ceftazidime, ciprofloxacin, and azithromycin on the hemagglutination (HA) and adherence ability of 29 P-fimbriated Escherichia coli strains to the buffalo green monkey kidney (BGMK) cell line was investigated. Comparisons were...

...M. Extermann; C. Regamey; L. Humair; F. Murisier; K. Rhyner; H.-M. Vonwiller We conducted a prospective, randomized, multicentric study in community hospitals. Patients with clinical sepsis, rectal temperature ≥38°C and pulse rate ≥100bpm were randomized to receive ceftazidime (group CAZ...

...M. Dan; D. Zabeeda; F. Poch Serum levels and serum bactericidal activities of six antipseudomonal agents were studied comparatively in 60 patients. Single intravenous doses of gentamicin (1.5 mg/kg), piperacillin (4 g), ceftazidime (1 g), imipenem (0.5 g), aztreonam (1 g), and ciprofloxacin (200 mg...

...Franco Leoni; Stefania Ciolli; Anna Pascarella; Rosa Fanci; Roberto Caporale; Pier Luigi Rossi Ferrini Results of antibiotic treatment in 144 febrile episodes during drug-induced granulocytopenia are reported. 63 episodes were treated with ceftazidime plus amikacin and 81 with ceftriaxone (CFX...

.... Susceptibility testing was done using new and investigational antibiotics (loracarbef, cefixime, cefpirome, desacetylcefotaxime, cefpodoxime, cefmetazole, cefepime, cefprozil, and fleroxacin) and commonly used antibiotics (ceftazidime, mezlocillin, piperacillin, ciprofloxacin, tobramycin, and amikacin...

...D. Bassetti; M. Cruciani; M. Solbiati; F. Rubini; L. Gandola; G. Valenti; M. De Palma; R. Corda; N. Carimeo Seventy-two hospitalized patients with pneumonia or bacteremia were randomly allocated to receive ceftriaxone 2 g once daily i.v. or ceftazidime 2 g twice a day i.v. At the end of the study...

...Luzius Schmid; Manuel Jeschko; Clive Wilder-Smith; Ursula Schafroth; Beat Thurlimann; Augusto Pedrazzini; Hansjörg Senn The efficacy and safety of the two antibiotic combinations, ceftazidime plus amikacin and ceftriaxone plus amikacin were compared in an open randomized trial. 100 episodes...

...R.F. Schell; M. Francisco; J.A. Bihl; J.L. LeFrock The activity of ceftazidime was compared with those of aztreonam, newer cephalosporins and Sch 29482 against nonfermentative gram-negative bacilli. Ceftazidime was consistently more active (MIC < 8 μg) against the nonfermenters. Only Fla...

..., was generally the most active quinolone and imipenem the most active β -lactam agent. 9 9 2009 Quinolones Ciprofloxacin Norfloxacin Abbott 56619 Abbott 56620 Imipenem Ceftazidime Piperacillin © 1986 S. Karger AG, Basel 1986 Copyright / Drug Dosage / Disclaimer Copyright: All rights...

...A.A. McColm; D.M. Ryan The concentrations of ceftazidime attained in cardiac and leg muscles of rabbits were compared after a single intramuscular injection of 100 mg/kg. Simultaneous measurements of muscle and muscle fluid over an 8-hour period showed that ceftazidime penetrated heart muscle more...

...Mitsuo Ohkawa; Takao Nakashima; Ryochu Shoda; Akiyoshi Ikeda; Matsuo Orito; Masaru Sawaki; Toshiaki Sugata; Masayoshi Shimamura; Shoji Hirano; Kazuo Okumura The pharmacokinetics of ceftazidime, a new cephalosporin antibiotic, were studied in 7 healthy volunteers and 32 patients with renal...

...Evelio J. Perea; Javier Ayarra; Mercedes C. Garcia Iglesias; Isabel García Luque; Jesus Loscertales We have studied the penetration of cefuroxime and ceftazidime into lung tissue of 40 patients subjected to pulmonary surgery. Samples of blood and lung tissue were taken 1 and 2 h after antibiotic...

...Walter H Traub; Dierk Bauer; Marlene Spohr Five antimicrobial drugs (ceftazidime, ciprofloxacin, imipenem, piperacillin and tobramycin) and two human, intravenously applicable, IgG immunoglobulin preparations (Psomaglobin®, Polyglobin N®) were examined alone and in various combinations...

...Asbjørn Digranes; William L. Dibb; Eva Benonisen The in vitro activity of ceftazidime has been compared with those of cephalothin, cefuroxime, and netilmicin against a variety of gram-positive and gram-negative bacteria in order to register sensitivity patterns in the western part of Norway...

...C. Costopoulos; N.J. Legakis; E. Papafragas; E. Marinis The in vitro antibacterial activity of eight newer β -lactam antibiotics (mecillinam, piperacillin, mezlocillin, cefoxitin, cefotaxime, moxalactam, ceftriaxone and ceftazidime) was determined against 87 cephalothin-resistant strains...

...Arantxazu Isla; Alicia R. Gascón; Javier Maynar; Alazne Arzuaga; José Antonio Sánchez-Izquierdo; José Luis Pedraz Background: Ceftazidime is a third-generation cephalosporin almost entirely eliminated by glomerular filtration and dose reductions are essential in patients with renal impairment...

...Pnina Chernobelski; Konstantin Lavrenkov; Doron Rimar; Klaris Riesenberg; Francisc Schlaeffer; Samuel Ariad; Wilmosh Mermershtain Purpose: It was the aim of this study to evaluate the results of a prospective study in a single medical center using ceftazidime monotherapy in cancer patients...