...Victoria Ferrari; Lucas Morand; Hervé Hyvernat; Renaud Schiappa; Jean Dellamonica; Nihal Martis Introduction: Our study aimed to identify relevant features associated with the reprisal of antineoplastic treatment in patients with solid cancers after unplanned admittance to the intensive care unit...

...Minas Sakellakis Background: Preclinical studies have suggested that metformin exerts antitumor effects on various types of cancers. However, the results of human clinical trials have been inconsistent. Summary: Metformin is widely considered to be a prime example of a clinically relevant compound...

...Takamasa Homma; Norio Yoshida; Kuniaki Tanaka; Masaya Isemura; Shota Torii; Teruhisa Kinoshita; Hideki Esaki; Takashi Sakakibara; Norio Takimoto Nivolumab, an immune checkpoint inhibitor (ICI), is now used to treat many advanced cancers, including non-small cell lung cancer (NSCLC) and renal cancer...

...Zeynep Gülsüm Güç; Ahmet Alacacıoğlu; Merve Güleç Yazır; Mehmet Eren Kalender; Sinan Ünal; Utku Oflazoğlu; Yaşar Yıldız; Tarık Salman; Yüksel Küçükzeybek; Hülya Ellidokuz; Mustafa Oktay Tarhan Objective: In this study, we aimed to assess anxiety and sleep quality in cancer patients treated...

... cells rely on aerobic glycolysis, through the Warburg effect. Summary: The pentose phosphate pathway (PPP) is a major glucose metabolic shunt that is upregulated in cancer cells. The PPP comprises an oxidative and a nonoxidative phase and is essential for nucleotide synthesis of rapidly dividing cells...

... aspects of human health. In fact, it is well known that diet can favour or not the development of various human pathologies, like diabetes, hypertension, and hypercholesterolaemia. Interestingly, diet has an influence in cancer development too (e.g., this relation has been studied for pancreatic, colonic...

...Mie Kotake; Tomohito Kuwako; Hisao Imai; Yoshio Tomizawa; Kyoichi Kaira; Akihiro Yoshii; Mai Ochiai; Yosuke Miura; Takashi Osaki; Reiko Sakurai; Kousuke Takei; Koichi Minato; Ryusei Saito Introduction: Treatment outcomes in patients with advanced non-small cell lung cancer (NSCLC) are poor due...

...Matteo Sarocchi; Eleonora Arboscello; Giorgio Ghigliotti; Roberto Murialdo; Claudia Bighin; Francesca Gualandi; Vera Sicbaldi; Manrico Balbi; Claudio Brunelli; Paolo Spallarossa Background: Patients developing cancer treatment-related left ventricular dysfunction (CTrLVD) require a prompt therapy...

... method is GFR estimation (eGFR) by formulae, hence the need to identify the formula with the best performance. Methods: Patients admitted between 2011 and 2017 and diagnosed with ovarian, endometrial, lung, esophageal, or testicular cancer were assessed retrospectively. The accuracy of the carboplatin...

... left ventricular ejection fraction (LVEF) is suspected to precede late cardiac events in cancer survivors treated by chemotherapy. We conducted the first multicenter study of early DD induced by chemotherapy. Patients who were candidates for standard dose chemotherapy were screened for the absence...

... permeabilization and the reduction of mitochondrial membrane potential induced by doxorubicin. Our findings suggest that bafilomycin A1 and chloroquine potentiate the anticancer effect of doxorubicin in hepatic cancer cells and that supplementation of conventional chemotherapy with lysosome inhibitors may provide...

...Perla Zgheib; Costantine F. Daher; Mohamad Mroueh; Anita Nasrallah; Robin I. Taleb; Mirvat El-Sibai Daucus carota (DC) is a herb used in folklore medicine in Lebanon to treat numerous diseases including cancer. Recent studies in our laboratory on DC oil and its fractions revealed potent anticancer...

...Antonia Digklia; Ioannis A. Voutsadakis Vascular thrombotic events are common in patients with cancer and chemotherapy is considered a contributing factor. Venous thrombotic events are more common than arterial ones which are less documented. In this report, we describe a patient with right...

...Yunfei Cao; Cun Liao; Aihua Tan; Lidan Liu; Feng Gao Background: Cetuximab is often used in patients with colorectal cancer, head and neck cancer, and other cancers. Hypomagnesemia is a major adverse event that was often ignored in studies. The aim of this meta-analysis is to gain a better...

...S.M. Hadi; M.F. Ullah; U. Shamim; S.H. Bhatt; A.S. Azmi Catalytic therapy is a cancer treatment modality based on the generation of reactive oxygen species (ROS) through administration of ascorbate/medicinal herbal extracts and copper. It is known that antioxidants such as ascorbate also exhibit...

... from any ideas, methods, instructions or products referred to in the content or advertisements. ATP Cancer Cisplatin Cytotoxicity Experimental Chemotherapy Chemotherapy 2010;56:1 8 DOI: 10.1159/000287351 Effect of Extracellular ATP on Cisplatin-Induced Cytotoxicity in Human Ovarian...

..., and confers a poor prognosis for this disease. Hemolytic-uremic syndrome Mitomycin C Pulmonary hemorrhage Cancer Clinical Report Chemotherapy 1993;39:453-456 R. Terra3 E. Poclv' A. Torrasa J.A. Bomb(b L. Reverta Nephrology, and Pathology Service, Hospital Clinic, Barcelona, Spain Pulmonary Hemorrhage...

..., etoposide and mitomycin C. The aim of this study was to investigate whether cancer patients who underwent polychemotherapy (n = 44) show more signs of oxidative stress in plasma than a group of healthy controls (n = 52). As an index of free radical generation, plasma concentrations of thiobarbituric-acid...

...Aws S. Salim The influence of scavengers of oxygen-derived free radicals on survival in colonic cancer was studied. Following curative surgery for carcinoma of the sigmoid colon at Dukes’ stage C, 198 patients making an uneventful recovery from surgery were randomized to the control group...

.... Nephrotoxicity Antibiotics Combination therapy Cancer Clinical Reports Chemotherapy 1991;37:287-291 ©1991 S. Karger AG, Basel 0009-3157/91/0374-0287 $2.75/0 Nephrotoxicity of Aminoglycosides, Polypeptides and Cephalosporins in Cancer Patients V. Krcme'ry, Jr., P. Fuchsberger, M. Gocâr, T. Salat, J...