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1-20 of 39
Keywords: 5-Fluorouracil
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Journal Articles
Journal:
Chemotherapy
Chemotherapy (2023) 68 (2): 95–101.
Published Online: 06 June 2023
.... 2022 5-Fluorouracil Dihydropyrimidine dehydrogenase Therapeutic drug monitoring Frail Elderly Adherence Adverse events Fluorouracil (5-FU) is a fluorinated pyrimidine that has been used since the mid-1950s to treat solid tumors and is still the backbone of chemotherapy...
Journal Articles
Journal:
Chemotherapy
Chemotherapy (2021) 66 (4): 139–155.
Published Online: 03 August 2021
... and contrast agent resulted in optimal suspension properties. Microspheres appeared circular with a smooth surface upon water adsorption. Microsphere embolism was observable in blood vessels of pathological sections. The surface of microspheres can adsorb 5-fluorouracil and arsenic trioxide...
Journal Articles
Dongyi Luo, Li Wang, Xinling Chen, Yiting Xiong, Fengming Yi, Jingli Ding, Hao Ding, Yiping Wei, Wenxiong Zhang
Journal:
Chemotherapy
Chemotherapy (2020) 65 (1-2): 11–20.
Published Online: 12 June 2020
...Dongyi Luo; Li Wang; Xinling Chen; Yiting Xiong; Fengming Yi; Jingli Ding; Hao Ding; Yiping Wei; Wenxiong Zhang Background: Platinum/S-1 (PS) and platinum/5-fluorouracil (PF) as first-line chemotherapies are extensively used for the treatment of advanced gastric or gastroesophageal junction cancer...
Journal Articles
Journal:
Chemotherapy
Chemotherapy (2016) 62 (1): 62–70.
Published Online: 20 September 2016
... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Advanced gastric cancer Capecitabine 5-Fluorouracil 5-FU S-1 Tegafur/gimeracil...
Journal Articles
Huapyong Kang, Jee Suk Chang, Tak Geun Oh, Moon Jae Chung, Jeong Youp Park, Seung Woo Park, Jinsil Seong, Si Young Song, Jae Bok Chung, Seungmin Bang
Journal:
Chemotherapy
Chemotherapy (2015) 60 (3): 191–199.
Published Online: 25 March 2015
...Huapyong Kang; Jee Suk Chang; Tak Geun Oh; Moon Jae Chung; Jeong Youp Park; Seung Woo Park; Jinsil Seong; Si Young Song; Jae Bok Chung; Seungmin Bang Objectives: To compare the efficacy of full-dose gemcitabine-based concurrent chemoradiotherapy (FG-CCRT) and conventional 5-fluorouracil CCRT (5FU...
Journal Articles
Ilkay Tugba Unek, Tarkan Unek, Ilhan Oztop, Tulay Akman, Koray Atilla, Hulya Ellidokuz, Seymen Bora, Sulen Sarioglu, Ugur Yilmaz
Journal:
Chemotherapy
Chemotherapy (2012) 58 (3): 233–240.
Published Online: 25 July 2012
... for advanced gastric cancer, but here we report this regimen combination in an adjuvant setting for the first time. Methods: Forty-eight patients with curatively resected gastric cancer were treated. Each 2-week cycle consisted of epirubicin (50 mg/m 2 ), cisplatin (50 mg/m 2 ), 5-fluorouracil (5-FU) IV bolus...
Journal Articles
Journal:
Chemotherapy
Chemotherapy (2010) 56 (4): 313–317.
Published Online: 13 August 2010
... and dihydropyrimidine dehydrogenase. Methods: Two patients with advanced gastric cancer and metastatic pancreatic cancer who received 5-fluorouracil-based chemotherapy presented with acute mental change and hyperammonemia. To evaluate the genetic background of the fluorouracil-associated hyperammonemic encephalopathy...
Journal Articles
Abdel-Moneim M. Osman, Samir F. Saad, Sherif Y. Saad, Abdel-Bast A. El-Aaser, Mahmoud M.E. El-Merzabani
Journal:
Chemotherapy
Chemotherapy (1994) 40 (4): 227–231.
Published Online: 11 September 2009
...Abdel-Moneim M. Osman; Samir F. Saad; Sherif Y. Saad; Abdel-Bast A. El-Aaser; Mahmoud M.E. El-Merzabani The pharmacokinetics of two commonly used anticancer drugs, methotrexate (MTX) and 5-fluorouracil (5-FU), were investigated in normal and bilharzial-infested mice. Liver glu-cose-6-phosphatase...
Journal Articles
Journal:
Chemotherapy
Chemotherapy (1994) 40 (6): 427–430.
Published Online: 11 September 2009
...S. Subramaniam; Shyama Subramaniam; M. Jagadeesan; Shyamala Devi Most of the breast cancer patients are treated with CMF which is a combination of three anticancer agents namely cyclophosphamide, methotrexate and 5-fluorouracil. The metabolites of CMF induce the level of lipid peroxides...
Journal Articles
Igor B. Shchepotin, Robert R. Buras, Russell J. Nauta, Mohsen Shabakang, Viatcheslav A. Soldatenkov, Stephen R.T. Evans
Journal:
Chemotherapy
Chemotherapy (1994) 40 (5): 348–356.
Published Online: 11 September 2009
...Igor B. Shchepotin; Robert R. Buras; Russell J. Nauta; Mohsen Shabakang; Viatcheslav A. Soldatenkov; Stephen R.T. Evans The purpose of this study was to assess the efficacy of verapamil (20 μ M ) and hyperthermia (42 °C) as modifiers of 5-fluorouracil (5-FU) used at different concentrations...
Journal Articles
Journal:
Chemotherapy
Chemotherapy (1988) 34 (6): 504–511.
Published Online: 09 September 2009
...S.S. Hussain; M.H. Amer; M.A. Hannan Cytotoxicity of cisplatin and carboplatin was compared using each drug alone and in combination with either 5-fluorouracil (5-FU) or methotrexate (MTX) and with 5-FU, vincristine (VCR) and bleomycin (BLM) together in the mouse embryo fibroblast line C3H10T...
Journal Articles
Journal:
Chemotherapy
Chemotherapy (1990) 36 (2): 147–154.
Published Online: 09 September 2009
... chemoresistance and/or to increase chemical cytotoxicity. Our results indicate that ozone in combination with 5-fluorouracil (5-FU) makes a 5-FU-resis-tant cell line susceptible for the combined treatment modality. Furthermore, ozone acts synergistically or at least additive to chemotherapy in different tumor...
Journal Articles
Journal:
Chemotherapy
Chemotherapy (1988) 34 (6): 484–489.
Published Online: 09 September 2009
...Yoshihiko Maehara; Tetsuya Kusumoto; Hiroko Kusumoto; Hideaki Anai; Keizo Sugimachi The sensitivity of human gastric cancer tissue to 5-fluorouracil (5-FU) and its analogues l-(2-tetrahydrofuryl)-5-fluorouracil (FT), UFT and 1-hexylcarbamoyl-5-fluorouracil (HCFU) was determined, using the in vivo...
Journal Articles
Journal:
Chemotherapy
Chemotherapy (1979) 25 (2): 70–76.
Published Online: 08 September 2009
...T.K. Basu; M. Aksoy; J.W.T. Dickerson The effect of 5-fluorouracil on the thiamin status of normal female adult rats has been investigated. Pre-treatment of the animals with the cytotoxic drug daily for 3 successive days resulted in a significant decrease in hepatic concentrations of thiamin...
Journal Articles
Journal:
Chemotherapy
Chemotherapy (2009) 55 (3): 137–144.
Published Online: 06 April 2009
... induced by cisplatin and 5-fluorouracil (cis + 5-FU) in carcinoma-bearing mice. Methods: Apoptosis was studied by annexin V-propidium iodide method. Total white blood cell count was performed using 3% glacial acetic acid on hemocytometer. Cytotoxicity was determined by LDH release assay and T/NK cell...
Journal Articles
Efraim Idelevich, Franklin Greif, Eli Mavor, Rafael Miller, Hanoch Kashtan, Sergo Susmalian, Arie Ariche, Baruch Brenner, Noa Ben Baruch, Michael Dinerman, Adi Shani
Journal:
Chemotherapy
Chemotherapy (2009) 55 (2): 76–82.
Published Online: 12 December 2008
...: Thirty-one patients with non-resectable, colorectal cancer (CRC) liver metastases received irinotecan 120 mg/m 2 , followed by leucovorin (LV) 20 mg/m 2 and 5-fluorouracil (5-FU) 500 mg/m 2 administered by HAI every 2 weeks, plus UFT (tegafur-uracil) 200 mg/m 2 /day with LV 30 mg/day on days 1–22...
Journal Articles
Ryuji Yasumatsu, Torahiko Nakashima, Hideoki Uryu, Toranoshin Ayada, Takahiro Wakasaki, Ryunosuke Kogo, Muneyuki Masuda, Masakazu Fukushima, Shizuo Komune
Journal:
Chemotherapy
Chemotherapy (2008) 55 (1): 36–41.
Published Online: 21 November 2008
...Ryuji Yasumatsu; Torahiko Nakashima; Hideoki Uryu; Toranoshin Ayada; Takahiro Wakasaki; Ryunosuke Kogo; Muneyuki Masuda; Masakazu Fukushima; Shizuo Komune Background: 5-Fluorouracil (5-FU) is a widely used drug in head and neck squamous cell carcinoma (HNSCC). Thymidylate synthase (TS), which...
Journal Articles
Shigemi Matsumoto, Takafumi Nishimura, Masashi Kanai, Yukiko Mori, Satoshi Nagayama, Jun’ichiro Kawamura, Akinari Nomura, Shin’ichi Miyamoto, Toshiyuki Kitano, Hiroshi Ishiguro, Kazuhiro Yanagihara, Satoshi Teramukai, Yoshiharu Sakai, Tsutomu Chiba, Masanori Fukushima
Journal:
Chemotherapy
Chemotherapy (2008) 54 (5): 395–403.
Published Online: 09 September 2008
... of FOLFOX regimens (5-fluorouracil and L -leucovorin combined with oxaliplatin) are widely used for the treatment of advanced colorectal cancer, the neurotoxicity caused by oxaliplatin is often problematic. The aim of this observational study was to assess the safety and efficacy of a modified version...
Journal Articles
Journal:
Chemotherapy
Chemotherapy (2008) 54 (5): 357–363.
Published Online: 05 September 2008
... (HK) II, a key glycolytic enzyme, may enhance the activity of anticancer drugs. The aim of this study was to investigate the effect and mechanisms of HK II on chemosensitivity of a colon cancer cell line (LoVo) to 5-fluorouracil (5-FU). Methods: HK II gene expression was downregulated by RNA...
Journal Articles
Nisana Namwat, Piyawan Amimanan, Watcharin Loilome, Patcharee Jearanaikoon, Banchob Sripa, Vajarabhongsa Bhudhisawasdi, Wichittra Tassaneeyakul
Journal:
Chemotherapy
Chemotherapy (2008) 54 (5): 343–351.
Published Online: 21 August 2008
...Nisana Namwat; Piyawan Amimanan; Watcharin Loilome; Patcharee Jearanaikoon; Banchob Sripa; Vajarabhongsa Bhudhisawasdi; Wichittra Tassaneeyakul Background: Although 5-fluorouracil (5-FU) is the drug of choice for the palliative treatment of cholangiocarcinoma (CCA), resistance to the drug...
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