...Bamidele T. Odumosu; Bola A. Adeniyi; Ram Chandra Background: The characterization of β-lactamase production in Pseudomonasaeruginosa is rarely reported in Nigeria. The objective of this study was to investigate the occurrence and characterize the different β-lactamases as well as mechanisms...

...R. Edwards; J. Brown; D. Greenwood The activity of meropenem was similar to that of imipenem against 88 clinical isolates of Bacteroides spp., including 28 non- fragilis strains. Four of the isolates were able to hydrolyse cephamycins or penems. Investigation of β-lactamases from these strains...

...Wolfgang Cullmann; Wolfgang Dick Twenty Pseudomonas maltophilia isolates were examined for susceptibility to β-lactam antibiotics, including carbapenems, and for β-lactamase production. All the isolates were resistant to imipenem (MICs 64–512 mg/l) and to a lesser extent, to meropenem (MICs 16–256...

... susceptibility test towards 12 β -lactam antibiotics. The β -lactamase activity of the strains was also examined by a sensitive modification of the chromogenic cephalosporin test. The strains of P. aeruginosa could not be clover-leaf tested as they inhibited the indicator strains. All the Enterobacteriaceae...

...W. Cullmann; W. Opferkuch; M. Stieglitz; W. Dick The activity of 9 recently developed β -lactam compounds was evaluated in 185 ampicillin-resistant isolates of Enterobacteriaceae. Moreover, in all strains, spontaneous and inducible β -lactamase production was quantified and correlated...

...A.D. Russell; P.C. Tottle Cefuroxime, a new cephalosporin antibiotic, was inhibitory at low concentrations to several types of gram-negative bacteria. It was considerably more stable than cephaloridine or cephalothin to the β -lactamases produced by Escherichia coli (RP1), Klebsiella aerogenes K1...

...Frédéric Bert; Catherine Branger; Nicole Lambert-Zechovsky Background: Ticarcillin resistance in Pseudomonas aeruginosa can be mediated by various β-lactamases of the CARB and OXA groups. Methods: We investigated the activity of seven β-lactam agents and two β-lactam-β-lactamase inhibitor...