.... aequinoctialis . In addition, FISH mapping of telomeric sequences revealed signals in the collochores, raising several questions on the chromosomal evolution in this group. For O. abbreviata , a karyotype composed of 22 chromosomes and a karyotype formula of 2n = 22 = 20 + X + y (Fig. 1 ) was found...

... of telomere dysfunction in these patient groups to study the correlation between telomere length and the progression of NAFLD. We analyzed peripheral lymphocytes from 22 patients with NAFLD, 20 patients with CC, and 20 healthy, age-matched controls. Telomere length was analyzed using quantitative fluorescence...

... on the species. Fluorescence in situ hybridization with a (TTAGG) n telomeric motif probe revealed terminal signals, matching those of the Cot DNAs obtained from each species, that were also restricted to the terminal regions of all chromosomes. Dot blot analysis with the Cot fraction from M. quadripunctata...

... with telomeric probe revealed an exclusively terminal position of telomeric sequences in L. jicari (2n = 42 chromosomes in females), but extensive interstitial signals, potentially remnants of chromosomal fusions, in L. burtonis (2n = 34 in females). Our study shows that even largely differentiated...

... , Eligmodontia puerulus, and E. morgani are polymorphic for Robertsonian translocations, whereas Salinomys delicatus possesses XX/ XY 1 Y 2 sex chromosomes. Telomeric signals were detected at both ends of all chromosomes of the studied species. In S. delicatus interstitial telomeric sequences (ITS) were observed...

... = 62-64 and 8 pairs of macrochromosomes. A distinct feature was a sharp macro-microchromosome boundary. Telomeric sequences were present at all chromosome ends and interstitially in PER2q, the latter coinciding with a C-band. NORs mapped to 4 pairs of microchromosomes which is in contrast to a single...

... determination have been reported in this group, and female heterogamety was known only in distantly related gecko families separated from the pygopodoid geckos around 150 million years ago. The W chromosome in U. milii is highly heterochromatic and contains a large number of telomeric-like repeats comparable...

...K. Thomay; A. Schienke; B. Vajen; U. Modlich; A. Schambach; W. Hofmann; B. Schlegelberger; G. Göhring The fate of cultivated primary hematopoietic stem cells (HSCs) with respect to genetic instability and telomere attrition has not yet been described in great detail. Thus, knowledge of the genetic...

...K. Ocalewicz In fishes, as in other vertebrate species, the DNA component of the telomeres consists of the tandemly repeated TTAGGG motif. The length of the telomeric arrays in fishes ranges from 2 to 25 kb and shortens with age in some of the species. To date, chromosomal distribution...

..., TTAGGG n sequence and non-LTR retrotransposon family members Rex1, Rex3 and Rex6 showed that non-LTR elements may be dispersed in the chromosome set with relative concentration in heterochromatic regions, as shown by Rex1 , or may even intercalate in 45S rDNA and the telomeric sequence, as found for Rex3...

... but not on the Y chromosome, making it unlikely that rDNA contributed to the elongation of the Y chromosome; recent end-to-end fusion also seems unlikely given the lack of interstitial telomeric signals. GISH with different concentrations of female blocking DNA detected a possible pseudo-autosomal region on the Y...

... chromosome fragments. Remnants of the irradiated chromosomes had different sizes, and their number varied intraindividually from 1 to 15. To efficiently pass through the series of the cell divisions, such chromosome fragments must have had functional kinetochores. Distribution patterns of the telomeric...

...; Schmid et al., 2010]. Paternal introgression AFLP Asexual reproduction B chromosomes Gynogenesis Microdissection Telomeres Table 1 Microchromosome-specific sequence from Poecilia formosa gained by AFLP The microchromosomes of P. formosa are small, dot-like chromosomes...

...R. Sukenik-Halevy; T. Biron-Shental; R. Sharony; M.D. Fejgin; A. Amiel Individuals with trisomy 21 have an increased risk of developing leukemia and premature dementia. They also have a higher rate of telomere loss. The aim of the study was to compare telomere length and the hTERC gene copy number...

... authors. Interestingly, many of the distal chromosome segments in T. virginiana possess duplicated subterminal telomere clusters, heterochromatin, 5S and 45S rDNAs orderly intermixed and share this complex cytomolecular architecture with the common type of a B chromosome. Based on the obtained results...

... development of ultra-resolution three-dimensional and live microscopy methods. Studies conducted so far indicate that different chromosome regions exhibit different dynamics patterns in early prophase. In many species telomeres cluster at the nuclear envelope at the beginning of zygotene forming the telomere...