...-1145A22, 7q31.1) as previously described [Romana et al., 1994]. Mosaic 7q22q31 Array-CGH Neocentromere Small supernumerary marker chromosome Supernumerary ring chromosomes (SRC) constitute about 10% of small supernumerary marker chromosomes (sSMC) [Blennow et al., 1994]. These small SRC...

...Madhavan Jeevan Kumar; Rangasamy Ashok Kumar; Venugopal Subhashree; Thanikachalam Jayasudha; Venkatasubramanian Hemagowri; Teena Koshy; Kalpana Gowrishankar A neocentromere is a functional centromere that has arisen within a region not known to have a centromere. We present a case with a very...

...E. Klein; M. Rocchi; A. Ovens-Raeder; N. Kosyakova; A. Weise; M. Ziegler; M. Meins; S. Morlot; W. Fischer; M. Volleth; A. Polityko; C. Mackie Ogilvie; C. Kraus; T. Liehr Since the first report in 1993, an ectopic centromere, i.e. neocentromere formation, has been reported in more than 100 small...

... length of the chromosomes and the formation of an inversion loop was not observed. We hypothesise that a possible mechanism leading to the change in centromere position is the repositioning and/or generation of a neocentromere. Despite the great similarity in the karyotypes of these sibling species...

... sequences in that constriction. Because of its stable mitotic distribution, a de novo formation of a neocentromere has to be assumed. A cytogenetic prenatal diagnosis on fetal amniotic cells was performed because of an elevated blood serum AFP concentration in the mother and led to the detection...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. CENP-A Centromere Genome dominance Neocentromere Satellite Somatic cell...

...M. Cuacos; M. González-García; M. González-Sánchez; M.J. Puertas; J.M. Vega An interstitial constriction located on the long arm of rye chromosome 5R (5RL) shows neocentromeric activity at meiosis. In some meiocytes this region is strongly stretched orienting with the true centromere to opposite...

... of a neocentromere, even though alpha-satellite sequences still appeared at the normal location. Chromosome analysis of the phenotypically normal father revealed the same deleted chromosome 8, as well as an apparently balancing mosaic marker chromosome 8. FISH studies revealed that the majority of the chromosome 8...

...V. Schubert Classical neocentromeres, proven mainly in Poaceae species, cause meiotic drive in higher plants. Here I present data indicating that the morphological stretching of a chromatin domain at the long arm of Aegilops markgrafii chromosome E during meiosis is not due to a supposed neocentric...

...T. Liehr; N. Kosyakova; A. Weise; M. Ziegler; G. Raabe-Meyer According to cytogenetic and molecular cytogenetic characterization, an otherwise not-altered chromosome 7 formed a neocentromere in band 7q32.1 in a clinically normal female. The alpha satellite sequence D7Z1 remained in its place...

..., EAS) chromosome 16 and in E. burchelli (Burchell’s zebra, EBU) chromosome 17 , confirming that centromere repositioning is a strikingly frequent phenomenon in this genus. The observation that the neocentromeres in EAS16 and EBU17 are in the same chromosomal position suggests that they may derive from...

.... Neocentromere Small supernumerary marker chromosome (sSMC) Y chromosome A review of the available literature on small supernumerary marker chromosomes (sSMC) revealed that there are at present 94 neocentric sSMC cases reported [Liehr et al., 2007; Liehr, 2009]. Of all these neocentrics none have yet...

...C.N. Topp; R.J. Okagaki; J.R. Melo; R.G. Kynast; R.L. Phillips; R.K. Dawe We report a neocentromere event on maize chromosome 3 that occurred due to chromosome breakage. The neocentromere lies on a fragment of the short arm that lacks the primary centromere DNA elements, CentC and CRM...