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Journal Articles
Subject Area:
Genetics
Cytogenet Genome Res 1.
Published Online: 23 February 2024
... Keywords: Ag-NOR, C-band, chromosomal rearrangements, chromosomes, G-band, tuco-tuco 2 Abstract Introduction Its wide karyotypic variation characterizes the genus Ctenomys, and in Brazil, the genus is distributed in the country s southern, Midwest, and Northern regions. Recently, populations of Ctenomys...
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Journal Articles
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Enhancer activities of the three  Sox9  enhancers. Comparison of the enhanc...
Published Online: 20 January 2024
Fig. 1. Enhancer activities of the three Sox9 enhancers. Comparison of the enhancer activities of ( a ) Enh8, ( b ) Enh14, and ( c ) Enh13 in COS7 cells co-transfected with or without NR5A1, mSRY, mSOX9, and tosSOX9. * p < 0.001, ** p < 0.05. More about this image found in Enhancer activities of the three Sox9 enhancers. Comparison of the enhanc...
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In vitro reporter gene assay using reporter vectors in which the partial se...
Published Online: 20 January 2024
Fig. 2. In vitro reporter gene assay using reporter vectors in which the partial sequences of tosEnh13 were replaced with mouse sequences. a Schematic map of the reporter vector. In tosEnh13_L (blue), the initial 200 bp is from tosEnh13 and the latter 430 bp is from mEnh13. tosEnh13_R (orange... More about this image found in In vitro reporter gene assay using reporter vectors in which the partial se...
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In vitro reporter gene assay using reporter vectors in which the partial se...
Published Online: 20 January 2024
Fig. 3. In vitro reporter gene assay using reporter vectors in which the partial sequences in the second half of tosEnh13 were replaced with mouse sequences. a Schematic map of the reporter vector. In tosEnh13_LL (green), the initial 300 bp is from tosEnh13 and the latter 330 bp is from mEnh1... More about this image found in In vitro reporter gene assay using reporter vectors in which the partial se...
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In vitro reporter gene assay using reporter vectors in which the tosEnh13 s...
Published Online: 20 January 2024
Fig. 4. In vitro reporter gene assay using reporter vectors in which the tosEnh13 sequence was gradually reduced in the final 330 bp. a Schematic map of the reporter vector. In tosEnh13_R1 (brown), R2 (beige), R3 (yellow), R4 (blue), and R5 (purple), the latter 216, 197, 146, 80, and 49 bp ar... More about this image found in In vitro reporter gene assay using reporter vectors in which the tosEnh13 s...
Journal Articles
Subject Area:
Genetics
Cytogenet Genome Res 1–11.
Published Online: 11 January 2024
..., and Raca Gordana for their advice, the ISCN Standing Committee members, and the OGM user group members for their comments. This is not a research study, nor does it involve human subjects, so there is no need for informed consent or ethical approval. The authors have no conflicts of interest...
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Schematic representation of a chromosomal insertion identified by ogm (Cour...
Published Online: 11 January 2024
Fig. 2. Schematic representation of a chromosomal insertion identified by ogm (Courtesy of Dr. H. Barseghyan). *Variable size refers to the insertion-specific distance between points A and B. More about this image found in Schematic representation of a chromosomal insertion identified by ogm (Cour...
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Flow diagram illustrates selection of study participants. After exclusion o...
Published Online: 21 December 2023
Fig. 1. Flow diagram illustrates selection of study participants. After exclusion of unaffected relatives, individuals without 45,X karyotypes, and individuals without molecular data, a total of 29 subjects were included in the final analysis. More about this image found in Flow diagram illustrates selection of study participants. After exclusion o...
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a  Total number of mutations observed in both complete remission and non-re...
Published Online: 10 December 2023
Fig. 1. a Total number of mutations observed in both complete remission and non-responder cohort ( n = 751), distribution of mutations in genes screened. b Distribution of mutation subtypes (termination, start loss, and missense) observed in all genes. More about this image found in a Total number of mutations observed in both complete remission and non-re...
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a  Mutations observed in complete remission cohort.  b  Mutations observed ...
Published Online: 10 December 2023
Fig. 2. a Mutations observed in complete remission cohort. b Mutations observed in non-responder cohort. c Violin plot of distribution of allele frequency of mutations screened in the genes. More about this image found in a Mutations observed in complete remission cohort. b Mutations observed ...
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Mutations observed in immune escape genes, transcription factors and NOTCH ...
Published Online: 10 December 2023
Fig. 5. Mutations observed in immune escape genes, transcription factors and NOTCH pathways. IRF4 ( a ), EZH 2 ( b ), MYC ( c ), B2M ( d ), CD58 ( e ), and NOTCH1 ( f ) truncating mutations in the intracellular domain. More about this image found in Mutations observed in immune escape genes, transcription factors and NOTCH ...
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Structural and physicochemical analysis of the AlphaFold-modeled wild-type ...
Published Online: 06 December 2023
Fig. 1. Structural and physicochemical analysis of the AlphaFold-modeled wild-type ZBTB18 protein and the AlphaFold-modeled missense variant p.(His47Gln). Fragment comprising residue 47 is highlighted to better visualize its hydrogen bond interactions and surface properties. More about this image found in Structural and physicochemical analysis of the AlphaFold-modeled wild-type ...