...Dongcai Wu; Li Shi; Fangrong Chen; Qing Lin; Jiao Kong MicroRNA-141 (miR-141-3p) is upregulated in preeclampsia. This study investigated the effect of methylation of the miR-141-3p promoter on cell viability, invasion capability, and inflammasomes in vitro. The expression of miR-141-3p...

... on epigenetic processes like gene promoter methylation of CpG islands. In the present study, the methylation status of the RAD21 gene is studied and associated with cytogenetic findings in CLL patients in order to investigate its possible implication in CLL pathogenesis and the formation of CLL chromosomal...

...Rui Fan; Shuqi Mao; Fade Zhong; Minli Gong; Fengying Yin; Lingmei Hao; Lina Zhang The purpose of the present study was to investigate whether methylation of the angiotensin II type 1 receptor (AGTR1) promoter contributed to the risk of essential hypertension (EH). A total of 96 EH cases and 96...

... of markers. The methylation status of the mismatch repair system was ascertained using the SALSA® MS-MLPA® methylation-specific DNA detection. The mismatch repair proteins MLH1, MSH2, MSH6, and PMS2 were evaluated by immunohistochemical staining. A total of 530 colorectal cancers were studied for MSI...

...., 2003; Han et al., 2005; Tate et al., 2009], changes in epigenetic marks, such as cytosine methylation [Shaked et al., 2001; Madlung et al., 2005; Lavania et al., 2012], the activation of transposons [Kashkush et al., 2003; Madlung et al., 2005; Chen et al., 2008; Kraitshtein et al., 2010; Petit et al...