...Takuya Hayakawa; Rino Suzuki; Kazuhiro Kagotani; Katsuzumi Okumura; Shin-ichiro Takebayashi E/L Repli-seq is a powerful tool for detecting cell type-specific replication landscapes in mammalian cells, but its potential to monitor DNA replication under replication stress awaits better understanding...

... to visualize in situ specific repeats, histone marks, and DNA replication sites, respectively. The effects of the non-denaturing RGEN-ISL and standard denaturing FISH on the chromatin structure were compared using super-resolution microscopy. 3D structured illumination microscopy revealed that denaturation...

... analyses after inhibition of DNA replication with aphidicolin. Inhibition of DNA replication had no effect on abnormal methylation and hydroxymethylation patterns that still persisted in the superovulated group. Interestingly, the onset of DNA replication, which was also analyzed in these experiments...

.... Arabidopsis Cell cycle Chromatin DNA replication Epigenetics Gene expression Histone H3 Plant The first scientist who described and named histones was Albrecht Kossel, who isolated them from bird erythrocytes more than a century ago and erroneously believed they were present only in some cell...