Sixteen male Podolian cattle, two sires and their 14 male offspring, were investigated cytogenetically on the basis of a female-like phenotype found in one of them. Eleven male offspring, including the one with female traits, and one of the two sires were found to carry an abnormal Y chromosome which originated from a pericentric inversion of the proximal half of the Yq arm (Yq11→q12.2), as demonstrated by both banding and FISH mapping techniques with Y-specific molecular markers.    

Cui X, Kato Y, Sato S, Sutou S: Mapping of bovine SRY gene on the distal tip of the long arm and murine SRY on the short arm of the Y chromosome by the method of fluorescence in situ hybridization (FISH). Anim Sci Technol 66:441–444 (1995).
Di Meo GP, Perucatti A, Iannuzzi L, Rangel-Figueiredo MT, Ferrara L: Constitutive heterochromatin polymorphism in river buffalo chromosomes. Caryologia 48:137–145 (1995).
Eggen A, Gautier M, Billaut A, Petit E, Hayes H, Laurent P, Urban C, Pfister-Genskow M, Eilertsen K, Bishop MD: Construction and characterization of a bovine BAC library with four genome-equivalent coverage. GSE 33:543–548 (2001).
Gustavsson I: Chromosome aberrations and their influence on the reproductive performance of domestic animals – a review. Z Tierzucht Zuchtbiol 97:176–195 (1980).
Hayes H, Petit E, Dutrillaux B: Comparison of RBG-banded karyotypes of cattle, sheep, and goats. Cytogenet Cell Genet 57:51–55 (1991).
Hayes H, Di Meo GP, Gautier M, Laurent P, Eggen A, Iannuzzi L: Localization by FISH of the 31 Texas nomenclature type I markers to both Q- and R-banded bovine chromosomes. Cytogenet Cell Genet 90:315–320 (2000).
Iannuzzi L: G- and R-banded prometaphase karyotypes in cattle (Bos taurus L.). Chrom Res 4:448–456 (1996).
Iannuzzi L, Di Meo GP: Chromosomal evolution in bovids: a comparison of cattle, sheep and goat G- and R-banded chromosomes and cytogenetic divergences among cattle, goat and river buffalo sex chromosomes. Chrom Res 3:291–299 (1995).
Iannuzzi L, Di Meo GP, Perucatti A, Incarnato D, Schibler L, Cribiu EP: Comparative FISH-mapping of bovid X chromosomes reveals homologies and divergences between the subfamilies Bovinae and Caprinae. Cytogenet Cell Genet 89:171–176 (2000).
ISCNDB 2000: International System for Chromosome Nomenclature of Domestic Bovids, Di Berardino D, Di Meo GP, Gallagher DS, Hayes H (eds), Iannuzzi L (co-ordinator). Cytogenet Cell Genet 92:283–299 (2001).
Jobling MA, Tyler-Smith C: New uses for new haplotypes: the human Y chromosome, disease and selection. Trends Genet 16:356–362 (2000).
Piumi F, Schibler L, Vaiman D, Oustry A, Cribiu EP: Comparative cytogenetic mapping reveals chromosome rearrangements between the X chromosomes of two closely related mammalian species (cattle and goats). Cytogenet Cell Genet 81:36–41 (1998).
Popescu CP: New data on pericentric inversion in cattle (Bos taurus L.). Ann Génét Sél Anim 8:443–448 (1976).
Robinson TJ, Harrison WR, Ponce de Leon FA, Davis SK, Elder FFB: A molecular cytogenetic analysis of the X chromosome repatterning in the Bovidae: transpositions, inversions, and phylogenetic inference. Cytogenet Cell Genet 80:179–184 (1998).
Switonsky M: A pericentric inversion in an X chromosome in the cow. J Herd 78:58–59 (1998).
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