Cytogenetic evaluation of young bulls of the Polish Holstein-Friesian breed, tested before approving for use in artificial insemination, revealed a carrier of a Y-autosome reciprocal translocation. The applied chromosome banding techniques and fluorescence in situ hybridization (FISH), with the use of locus-specific BAC probes, facilitated description of the translocation as t(Y;21)(p11;q11). The bull presented normal development, including body weight and the size of testicles, as well as libido. Testosterone concentration at the age of 8 months was similar in the carrier and a normal bull of the same age, but at the age of 12 months the testosterone concentration appeared to be lower in the carrier.

1.
Ashwell MS, Ashwell CM, Garrett WM, Bennett GL: Isolation, characterization and mapping of the bovine signal peptidase subunit 18 gene. Anim Genet 32:232–233 (2001).
2.
Citek J, Rubes J, Hajkova J: Short communication: Robertsonian translocations, chimerism, and aneuploidy in cattle. J Dairy Sci 92:3481–3483 (2009).
3.
De Lorenzi L, Molteni L, Denis C, Eggen A, Parma P: A new case of centric fusion in cattle: rob(21;23). Anim Genet 39:454–455 (2008).
4.
Ducos A, Berland HM, Bonnet N, Calgaro A, Billoux S, et al: Chromosomal control of pig populations in France: 2002–2006 survey. Genet Sel Evol 39:583–597 (2007).
5.
Ducos A, Revay T, Kovacs A, Hidas A, Pinton A, et al: Cytogenetic screening of livestock populations in Europe: an overview. Cytogenet Genome Res120:26–41 (2008).
6.
Iannuzzi L, Molteni L, Di Meo GP, De Giovanni A, Perucatti A, et al: A case of azoospermia in a bull carrying a Y-autosome reciprocal translocation. Cytogenet Cell Genet 95:225–227 (2001a).
7.
Iannuzzi L, Di Meo GP, Perucatti A, Eggen A, Incarnato D, et al: A pericentric inversion in the cattle Y chromosome. Cytogenet Cell Genet 94:202–205 (2001b).
8.
Iannuzzi L, Di Berardino D: Tools of the trade: diagnostics and research in domestic animal cytogenetics. J Appl Genet 49:357–366 (2008).
9.
Cribiu EP, Di Berardino D, Di Meo GP, Eggen A, Gallagher DS, et al: International System for Chromosome Nomenclature of Domestic Bovids (ISCNDB 2000). Cytogenet Cell Genet 92:283–299 (2001).
10.
Krumrych W: Overview of the cytogenetic evaluation of young bulls bred in the north western part of Poland in 1999–2008.Bull Vet Inst Pulawy 53:669–672 (2009).
11.
Liu WS, Ponce de Leon FA: Assignment of SRY, ANT3, and CSF2RA to the bovine Y chromosome by FISH and RH mapping. Anim Biotechnol 15:103–109 (2004).
12.
Molteni L, Perucatti A, Iannuzzi A, Di Meo GP, De Lorenzi L, et al: A new case of reciprocal translocation in a young bull: rcp(11;21)(q28;q12). Cytogenet Genome Res 116:80–84 (2007).
13.
Pinton A, Raymond Letron I, Berland HM, Bonnet N, Calgaro A, et al: Meiotic studies in an azoospermic boar carrying a Y;14 translocation. Cytogenet Genome Res 120:106–111 (2008).
14.
Rubes J, Pinton A, Bonnet-Garnier A, Fillon V, et al: Fluorescence in situ hybridization applied to domestic animal cytogenetics. Cytogenet Genome Res 126:34–48 (2009).
15.
Sasagawa I, Adachi Y, Kubota Y, Ishigooka M, Tomaru M, Nakada T: Hormone profiles and testicular histology in azoospermic men with Y-autosome translocation and autosomal translocation: Arch Androl 34:157–161 (1995).
16.
Switonski M, Andersson M, Nowacka-Woszuk I, Szczerbal I, Sosnowski J, et al: Identification of a new reciprocal translocation in an AI bull by synaptonemal complex analysis, followed by chromosome painting. Cytogenet Genome Res 121:245–248 (2008).
17.
Vallenzasca C, Martignoni M, Galli A: Finding of a bull with Y;17 translocation. Hereditas 113:63–67 (1990).
18.
Vialard F, Molina-Gomes D, Roume J, Podbiol A, Hirel C, et al: Case report: Meiotic segregation in spermatozoa of a 46,X,t(Y;10)(q11.2;p15.2) fertile translocation carrier. Reprod Biomed Online 18:549–554 (2009).
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.