Options of Interventional Pain Therapy for Tumor Patients About 60-90% of patients with advanced tumor stages suffer from pain. The underlying causes are frequently determined by tumor infiltrations in neighboring structures such as soft parts, bones, organs and nerves. In addition, specific tumor therapy, e.g. surgery, irradiation and chemotherapy,might give rise to pain syndromes. The increasing availability of retarded opioids in the last years and additional administration of co-analgesics according to the WHO guidelines has led to adequate pain control in the majority of cancer patients. However, some patients cannot be treated sufficiently or suffer from intolerable side effects. Therefore,interventional therapy concepts should be considered in early stages of an individual pain treatment strategy. Options of interventional pain therapy include blocking of peripheral nerves, subarachnoidal or epidural blockade techniques as well as modulations of the sympathetic nervous system. These techniques offer extended opportunities for pain relieve by direct application of local anesthetics, opioids and co-analgesics to relevant nerval structures. Moreover,thermal or chemical neurodestruction techniques might be beneficial for pain control. In particular, the neurodestruction of the plexus coeliacus for pain relieve in tumors and metastases of liver, pancreas, stomach, bowel and peritoneum is of high relevance interventional pain therapy. The following article gives an overview about possibilities and frequently applied techniques of interventional pain therapy.

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