A 53-year-old man was found to have a gallbladder tumor during a routine follow-up more than 10 years after nephrectomy for renal cell carcinoma in 1991. Computed tomography demonstrated a 2.5 × 2.5 cm pedunculated mass with strong contrast enhancement that was hypervascular on celiac angiography. Laparoscopic cholecystectomy was performed. The grossly resected surgical specimen contained two pedunculated polypoid tumors originating from muscular layer. The histopathology showed clear cell carcinomas that were predominantly below the mucosal layer. The cancer cells stained positive for glycogen and epithelial membrane antigen, but not for carcinoembryonic antigen, vimentin, or cytokeratin 7. The final pathologic diagnosis was gallbladder metastasis from renal cell carcinoma. Our case is only the 8th reported case of a solitary metastasis within the gallbladder from renal cell carcinoma.

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