Anhand eines Fallbeispieles eines 60jährigen Patienten mit phlegmonöser Entzündung der Fingerendglieder II und III rechts und fibrosierender Osteomyelitis im Rahmen einer Endangiitis obliterans wird die lokale Anwendung von Taurolin®-2%-Lösung adjuvant der chirurgischen Herdsanierung gezeigt. Aufgrund des schweren destruierenden Weichteilinfektes wurde anfänglich eine Grenzzonenamputation diskutiert, die jedoch nach täglicher Spülung und Instillation von Taurolidin vermieden werden konnte. Die Lokaltherapie einer feuchten Gangrän des 2.-4. Fingers links mittels isotoner Kochsalzlösung und enzymatischer Wundreinigung blieb bei ähnlicher Durchblutungs-situation über 15 Wochen erfolglos. Progredienter nekrotischer Zerfall und Handphlegmone erforderten mehrfache Nachresektionen und zwangen letztendlich zu einer Amputation des Mittelfingers. Taurolidin stellt im vorliegenden Fall eine wirkungsvolle adjuvante Therapie alternativ zu einer Vielzahl lokaler Antiseptika dar.

Keywords:
Taurolidin, Endangiitis obliterans, Osteomyelitis
This content is only available via PDF.
© 1994 S. Karger AG, Basel
1994
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.