Der Proktologe muβ besonders auf die Medikamente achten, die er seinen Patienten verschreibt. Dabei hat er die Absorptionsweise der Wirkstoffe, wie Anästhetika, Antiseptika, Steroide, Antikoagulantien, vasoaktive Substanzen oder Antibiotika, im Rektum, Analkanal und Perineum ebenso wie die galenischen Einschränkungen, die ihre Aktivität begrenzen, zu kennen. Die verschiedenen Medikamente können in Form von Suppositorien, Gels, Salben, Sprays, Schaum, Lösungen oder Feuchttüchlein verabreicht werden. Alle diese Präparate werden hinsichtlich ihrer Wirksamkeit und Indikation, aber auch ihrer Risiken diskutiert.

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