Die schweren Weichteilinfektionen sollten nach der Dringlichkeit ihrer chirurgischen Versorgung eingeteilt werden. Danach haben die nekrotisierende Fasziitis, die Fourniersche Gangrän, die Myonekrose des Gasbrandes und synergistischmikrobielle Gangräne die gröβte klinische Bedeutung. Im Vordergrund der Therapie steht das aggressive chirurgische Debridement mit programmierter chirurgischer Revision. Intensivmedizinische Maβnahmen und Antibiotika unterstützen die Behandlung. Nur bei guter Kenntnis der Erkrankung und adäquatem zügigem Vorgehen läβt sich die Letalität vermindern.

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