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Menglu Ouyang, Roland Faigle, Xia Wang, Brenda Johnson, Debbie Summers, Pooja Khatri, Laurent Billot, Hueiming Liu, Alejandra Malavera, Paula Muñoz-Venturelli, Francisca González, Francisca Urrutia, Diana Day, Lili Song, Yi Sui, Candice Delcourt, Thompson Robinson, Alice C. Durham, Ahtasam Ebraimo, Wan Asyraf Wan Zaidi, Stephen Jan, Richard I. Lindley, Victor C. Urrutia, Craig S. Anderson, the OPTIMISTmain Investigators
Cerebrovasc Dis 1–8.
Published Online: 26 October 2023
...; Wan Asyraf Wan Zaidi; Stephen Jan; Richard I. Lindley; Victor C. Urrutia; Craig S. Anderson; the OPTIMISTmain Investigators Introduction: Careful monitoring of patients who receive intravenous thrombolysis (IVT) for acute ischemic stroke (AIS) is resource-intensive, and potentially less relevant...
Chih-Hao Chen, Fouzi Bala, Mohamed Najm, Ibrahim Alhabli, Nishita Singh, Nima Kashani, Rosalie V. McDonough, MacKenzie Horn, Jilian Stang, Andrew M. Demchuk, Bijoy K. Menon, Michael D. Hill, Mohammed A. Almekhlafi
Cerebrovasc Dis 1–8.
Published Online: 26 July 2023
... between start of intravenous thrombolysis (IVT) to start of endovascular thrombectomy (EVT) on stroke outcomes. Methods: Data from the Quality Improvement and Clinical Research (QuICR) provincial stroke registry from Alberta, Canada, were used to identify stroke patients who received IVT and EVT from...
Sohei Yoshimura, Masatoshi Koga, Takashi Okada, Manabu Inoue, Kaori Miwa, Mayumi Fukuda-Doi, Rei Kondo, Takeshi Inoue, Masahiko Ichijo, Masafumi Ohtaki, Yoshinari Nagakane, Ryo Itabashi, Nobuyuki Sakai, Kazumi Kimura, Kenji Kamiyama, Yoshiaki Shiokawa, Yoshiki Yagita, Toru Iwama, Yusuke Yakushiji, Masayoshi Kusumi, Tetsu Yamaki, Jyunichi Uemura, Asuka Yasuura, Shouhei Noshiro, Daiki Fukunaga, Yukako Yazawa, Junya Aoki, Masaaki Yoshikawa, Masafumi Ihara, Kazunori Toyoda, for the THAWS trial investigators
Cerebrovasc Dis 1–8.
Published Online: 01 June 2023
.... The safety outcomes were symptomatic intracranial hemorrhage (sICH) after thrombolysis, all-cause deaths, and all adverse events. The efficacy outcomes were favorable outcome defined as an mRS score of 0–1 or recovery to the same mRS score as the premorbid score, complete independence defined as an mRS score...
Marlene Heinze, Bastian Cheng, Tae-Hee Cho, Martin Ebinger, Matthias Endres, Jochen B. Fiebach, Jens Fiehler, Josep Puig, Robin Lemmens, Vincent Thijs, Keith W. Muir, Norbert Nighoghossian, Alina Königsberg, Märit Jensen, Ewgenia Barow, Iris Lettow, Salvador Pedraza, Claus Z. Simonsen, Christian Gerloff, Götz Thomalla
Cerebrovasc Dis (2023) 52 (5): 560–566.
Published Online: 02 March 2023
... Gerloff; Götz Thomalla Introduction: The aims of this study were to evaluate the relationship of clinical and imaging baseline factors and treatment on the occurrence of early neurological improvement (ENI) in the WAKE-UP trial of MRI-guided intravenous thrombolysis in unknown onset stroke and to examine...
Cerebrovasc Dis (2023) 52 (5): 597–606.
Published Online: 14 December 2022
...Yaowen Hu; Junhui Su; Xinxin Cui; Lizhen Pan; Lingjing Jin; Fei Teng When spontaneous cervical spinal epidural hematoma (SCEH) presents with hemiparesis, it can be misdiagnosed with ischemic stroke (IS), and the treatment of IS such as thrombolysis may deteriorate the symptoms of patients with SCEH...
Cerebrovasc Dis (2023) 52 (4): 427–434.
Published Online: 21 October 2022
... large artery occlusion, who were treated with EVT and achieved successful reperfusion (thrombolysis in cerebral infarction grade 2b–3). The cerebral SVD burden was evaluated using baseline brain magnetic resonance imaging using a modified Fazekas score (mFS). The main outcome variable was FR, defined...
Carlos Delfino, Enrico Mazzon, Gabriel Cavada, Paula Muñoz Venturelli, Alejandro M. Brunser, Felipe Jurado Díaz, Lorena Lara Cisternas, Diego Rocha Jiménez, Mirya Arévalo Valdivia, Diego Rojas Torres, Eloy Mansilla
Cerebrovasc Dis (2022) 51 (5): 690–694.
Published Online: 07 April 2022
..., thrombolysis rate, stroke severity, and time from the stroke onset to hospital admission. Results: We observed that the number of stroke codes and the number of patients undergoing reperfusion therapy did not change significantly ( p = 0.669 and 0.415, respectively). No differences were found with respect...
Alis J. Dicpinigaitis, Kieran E. Palumbo, Chirag D. Gandhi, Jared B. Cooper, Simon Hanft, Haris Kamal, Steven D. Shapiro, Eric Feldstein, Martin Kafina, Christeena Kurian, Ji Y. Chong, Stephan A. Mayer, Fawaz Al-Mufti
Cerebrovasc Dis (2022) 51 (5): 565–569.
Published Online: 14 February 2022
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acute ischemic stroke Obesity Thrombectomy Thrombolysis Outcome Obesity has traditionally been considered a poor determinant of health . In the context...
Cerebrovasc Dis (2021) 50 (6): 666–680.
Published Online: 14 October 2021
.... The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2021 Stroke History Cerebral blood flow Neuroprotection Thrombolysis Mobile stroke unit...
Cerebrovasc Dis (2022) 51 (1): 60–66.
Published Online: 17 August 2021
...Ganesh Asaithambi; Xin Tong; Sallyann M. Coleman King; Mary G. George Background: Presentation with mild symptoms is a common reason for intravenous thrombolysis (IVT) nonuse among acute ischemic stroke (AIS) patients. We examined the impact of IVT on the outcomes of mild AIS over time. Methods...
Chen Chen, Xia Wang, Xiaoying Chen, Menglu Ouyang, Lingli Sun, Hisatomi Arima, Thompson Robinson, Richard I. Lindley, John Chalmers, Gang Li, Lili Song, Craig S. Anderson, for the ENCHANTED Investigators
Cerebrovasc Dis (2021) 50 (5): 560–566.
Published Online: 21 June 2021
... profile and management approaches, we aimed to determine disparities in clinical outcomes between Asian and non-Asian participants of the international, Enhanced Control of Hypertension and Thrombolysis Stroke study (ENCHANTED). Methods: ENCHANTED was a multicenter, prospective, partial-factorial...
Felix Schlachetzki, Sibylle Wilfling, Nikolai Dominik Hubert, Andrea Wagner, Roman L. Haberl, Ralf Andreas Linker, Gordian Jan Hubert
Cerebrovasc Dis (2021) 50 (3): 317–325.
Published Online: 04 February 2021
... (IS) and related consultations using the telestroke TEMPiS “working diagnosis” database prior (PL), within (WL), and after easing (EL) of CPL. Methods: Twelve hospitals were selected and data analyzed regarding IS (including intravenous thrombolysis [intravenous recombinant tissue plasminogen; IV rtPA...
Alan Flores, Xavier Ustrell, Laia Seró, Anna Pellisé, Paula Rodriguez, Jaume Viñas, Marc Ribó, Jurek Krupinski, Natalia Más, Sonia Garcia, Ernesto Palomeras Soler, Dolores Cocho, David Canovas, Francisco Purroy, Joaquim Serena, Jose Zaragoza-Brunet, Victor Obach, Natalia Perez de la Ossa, Pere Cardona, Carlos A. Molina, Sonia Abilleira, Marta Rubiera, on behalf of Catalan Stroke Code and Reperfusion Consortium
Cerebrovasc Dis (2020) 49 (5): 550–555.
Published Online: 22 October 2020
... stroke treated in clinical practice . JAMA . 2019 ; 322 ( 3 ): 252 – 63 . 10.1001/jama.2019.8286 . 6. Seners P , Turc G , Maïer B , Mas JL , Oppenheim C , Baron JC . Incidence and predictors of early recanalization after intravenous thrombolysis: a systematic...
Iris Q. Grunwald, Daniel J. Phillips, David Sexby, Viola Wagner, Martin Lesmeister, Monika Bachhuber, Shrey Mathur, Paul Guyler, James Fisher, Saman Perera, Stefan A. Helwig, Andrea Schottek, Ian Ewart, Nisha Menon, Muhammad Inam Ul Haq, Daniel Grün, Fatma Merzou, Caroline Howard, Sarah Mapplebeck, David Dommett, Sajid Alam, Annie Chakrabarti, Stephen Gerry, Chris Wiltshire, Marcus Bailey, Thomas Bertsch, Theresa Foster, Tom Davis, Wolfgang Reith, Klaus Fassbender, Silke Walter
Cerebrovasc Dis (2020) 49 (4): 388–395.
Published Online: 26 August 2020
...-hospital thrombolysis was administered to 8 of 28 (28.6%) ischaemic stroke patients. Pre-hospital diagnosis avoided hospital admission for 29 (25.0%) patients. As hospital treatment was indicated, 35 (30.2%) patients were directly triaged to the stroke unit, 1 patient (0.9%) even directly to the catheter...
Xiaoying Chen, Candice Delcourt, Lingli Sun, Zien Zhou, Sohei Yoshimura, Shoujiang You, Alejandra Malavera, Takako Torii-Yoshimura, Cheryl Carcel, Hisatomi Arima, Maree L. Hackett, Thompson Robinson, Lili Song, Xia Wang, Richard I. Lindley, John Chalmers, Craig S. Anderson, for the ENCHANTED Investigators
Cerebrovasc Dis (2020) 49 (4): 427–436.
Published Online: 22 July 2020
... of Hypertension and Thrombolysis Stroke Study (ENCHANTED). Methods: ENCHANTED was an international trial of low- versus standard-dose intravenous alteplase in AIS patients, with functional outcome (modified Rankin scale [mRS]) and HRQoL on the 5-dimension European Quality of Life Scale (EQ-5D) assessed at 90 days...
Cerebrovasc Dis (2020) 49 (2): 223–232.
Published Online: 24 April 2020
...Simone Vidale; Michele Romoli; Domenico Consoli; Elio Clemente Agostoni Background and Aim: The risk/benefit profile of intravenous thrombolysis (IVT) prior to endovascular thrombectomy (EVT) in acute ischemic stroke is still unclear. We provide a systematic review and meta-analysis including...
Xia Wang, Lili Song, Jie Yang, Lingli Sun, Tom J. Moullaali, Else Charlotte Sandset, Candice Delcourt, Richard I. Lindley, Thompson G. Robinson, Jatinder S. Minhas, Hisatomi Arima, John Chalmers, Jong S. Kim, Vijay Sharma, Ji-Guang Wang, Octávio Pontes-Neto, Pablo M. Lavados, Verónica V. Olavarría, Tsong-Hai Lee, Christopher Levi, Sheila O. Martins, Nguyen H. Thang, Craig S. Anderson, on behalf of the ENCHANTED Investigators
Cerebrovasc Dis (2020) 48 (3-6): 207–216.
Published Online: 06 December 2019
...; Tsong-Hai Lee; Christopher Levi; Sheila O. Martins; Nguyen H. Thang; Craig S. Anderson; on behalf of the ENCHANTED Investigators Objective: To determine the extent to which the effects of intensive blood pressure (BP) lowering are modified by doses of alteplase in thrombolysis-eligible acute ischemic...
Armin Marsch, Kosmas Macha, Gabriela Siedler, Lorenz Breuer, Erwin F. Strasser, Tobias Engelhorn, Arnd Dörfler, Stefan Schwab, Bernd Kallmünzer
Cerebrovasc Dis (2019) 48 (1-2): 17–25.
Published Online: 04 September 2019
... for thrombolysis, while high values >100 ng/mL excluded patients from recombinant tissue plasminogen activator use. For patients on VKAs, the cutoff was set at international normalized ratio of 1.7. Endovascular thrombectomy of a large vessel occlusion was performed independently from coagulation testing...
Sheryl Hui-Xian Ng, Alex W.K. Wong, Cynthia Huijun Chen, Chuen Seng Tan, Falk Müller-Riemenschneider, Bernard P.L. Chan, M. Carolyn Baum, Jin-Moo Lee, Narayanaswamy Venketasubramanian, Gerald Choon-Huat Koh
Cerebrovasc Dis (2019) 47 (5-6): 291–298.
Published Online: 21 August 2019
... stroke populations in Singapore and in St. Louis, USA, and to document thrombolysis rates and contrast factors associated with its uptake in both populations. Methods: The stroke populations described were from the Singapore Stroke Registry (SSR) in -Singapore and the Cognitive Rehabilitation Research...
Elena López-Cancio, Marc Ribó, Pere Cardona, Joaquín Serena, Francisco Purroy, Ernest Palomeras, Josep Maria Aragonès, Dolores Cocho, Moisés Garcés, Elsa Puiggròs, Iñigo Soteras, Ana Cabanelas, David Villagrasa, Ester Catena, Eduard Sanjurjo, Nuria López Claverol, Dolors Carrión, Mercè López, Sònia Abilleira, Antoni Dávalos, Natalia Pérez de la Ossa, on behalf of the Catalan Stroke Code and Reperfusion Consortium (Cat-SCR)
Cerebrovasc Dis (2018) 46 (1-2): 66–71.
Published Online: 22 August 2018
... Abilleira; Antoni Dávalos; Natalia Pérez de la Ossa; on behalf of the Catalan Stroke Code and Reperfusion Consortium (Cat-SCR) Objectives: The study aimed to evaluate the impact of a telestroke network on acute stroke care in Catalonia, by measuring thrombolysis rates, access to endovascular treatment...