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1-20 of 150
Keywords: Thrombolysis
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Journal Articles
Bridging Therapy versus Direct Mechanical Thrombectomy in Acute Basilar Artery Occlusion due to Different Stroke Etiologies
Available to PurchaseLigen Fan, Chuanyong Qu, Xiao Zhang, Xuemei Chen, Junlin Feng, Peng Chen, Zhiqiang Han, Wen Sun, Jinou Zheng
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2025)
Published Online: 14 February 2025
..., instructions or products referred to in the content or advertisements. 2025 Stroke Endovascular treatment Cardioembolism Atherosclerosis Thrombolysis Acute basilar artery occlusion (BAO) is one of the most devastating forms of stroke, leading to severe disability or death in up to 80...
Journal Articles
Ali Hammed, Almonzer Al-Qiami, Ahmad Alzawahreh, Josef Rosenbauer, Eman Ayman Nada, Zina Otmani, Nada G. Hamam, Asmaa Zakria Alnajjar, Elsayed Mohamed Hammad, Rawan Hamamreh, Karel Kostev, Gregor Richter, Christian Tanislav
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis 1–14.
Published Online: 24 August 2024
... stroke onset to groin puncture (MD of 9.91 min), it did not contribute to greater NIHSS improvement at 24 h and 7 days. Further trials with larger sample sizes are warranted to enhance precision in clinical guidance. Acute ischemic stroke Bridging therapy Mechanical thrombectomy Thrombolysis Meta...
Journal Articles
Predictors of Early versus Delayed Neurological Deterioration after Thrombolysis for Ischemic Stroke
Available to PurchaseQiao Han, Shoujiang You, Toshiki Maeda, Yanan Wang, Menglu Ouyang, Qiang Li, Lili Song, Yang Zhao, Xinwen Ren, Chen Chen, Candice Delcourt, Zien Zhou, Yongjun Cao, Chun-Feng Liu, Danni Zheng, Hisatomi Arima, Thompson G. Robinson, Xiaoying Chen, Richard I. Lindley, John Chalmers, Craig S. Anderson, Xia Wang
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2025) 54 (2): 175–183.
Published Online: 15 May 2024
...; Xia Wang Introduction: We aimed to determine predictors of early (END) and delayed neurological deterioration (DND) and their association with the functional outcome in patients with acute ischemic stroke (AIS) who participated in the international Enhanced Control of Hypertension and Thrombolysis...
Journal Articles
Menglu Ouyang, Francisca González, Michelle Montalbano, April Pruski, Stephen Jan, Xia Wang, Brenda Johnson, Debbie V. Summers, Pooja Khatri, Alejandra Malavera, Michael Iacobelli, Roland Faigle, Paula Munoz-Venturelli, Francisca Urrutia Goldsack, Diana Day, Thompson G. Robinson, Alice C. Durham, Ahtasam Ebraimo, Lili Song, Yi Sui, Wan Asyraf Wan Zaidi, Richard I. Lindley, Candice Delcourt, Victor Cruz Urrutia, Craig S. Anderson, Hueiming Liu
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2025) 54 (1): 96–104.
Published Online: 05 March 2024
... and safety of low-intensity versus standard monitoring in thrombolysis-treated patients with mild-to-moderate acute ischemic stroke (AIS). An embedded process evaluation explored integration and impact of the intervention on care processes at participating US sites. Methods: A mixed-methods approach...
Journal Articles
Intravenous Tenecteplase versus Alteplase before Mechanical Thrombectomy in Patients with Large Vessel Occlusion Stroke: A Systematic Review and Meta-Analysis
Available to PurchaseMohammed A. Almanna, Ziad S. Aloraini, Robert W. Regenhardt, Adam A. Dmytriw, Mohammed A. Bayounis, Mohammed A. Bin-Mahfooz, Yousef I. Alghamdi, Ysmeen T. Bucklain, Abdulrahman Y. Alhoumaily, Naif M. Alotaibi
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2025) 54 (1): 42–52.
Published Online: 15 February 2024
...; CHD, congestive heart disease; IVT, intravenous thrombolysis; MT, mechanical thrombectomy; SD, standard deviation; IQR, interquartile range. a Ostos et al. included bridging therapy who underwent MT as a subgroup analysis. Therefore, baseline characteristics could not be extracted. b Could...
Journal Articles
Intensive Blood Pressure Lowering and Renal Function in Ischemic Stroke Patients: Secondary Analysis of the ENCHANTED Trial
Available to PurchaseChen Chen, Xinwen Ren, Yang Zhao, Menglu Ouyang, Qiang Li Mbiostat, Xia Wang, Yunke Li, Shoujiang You, Yanan Wang, Thompson G. Robinson, Richard Lindley, Hisatomi Arima, John Chalmers, Gang Li, Xiaoying Chen, Craig S. Anderson, Lili Song, ENCHANTED Investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2024) 53 (6): 703–710.
Published Online: 17 January 2024
... is a major safety concern of intensive systolic blood pressure (SBP) lowering. We aimed to determine the effect of this treatment on early change in renal function in participants of the international Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED). Methods: Post hoc analysis...
Journal Articles
Radiographic Signs of Advanced Cerebral Venous Thrombosis Negatively Modulate the Effectiveness of Endovascular Treatments
Available to Purchase
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2024) 53 (5): 519–526.
Published Online: 06 November 2023
... to in the content or advertisements. 2023 Venous thrombosis Sinus Thrombectomy Thrombolysis Endovascular Hemorrhage Stroke Edema Cerebral venous thrombosis (CVT) is a potentially life-threatening cerebrovascular disease with limited treatment options [ 1, 2 ], and it has a predilection...
Journal Articles
Menglu Ouyang, Roland Faigle, Xia Wang, Brenda Johnson, Debbie Summers, Pooja Khatri, Laurent Billot, Hueiming Liu, Alejandra Malavera, Paula Muñoz-Venturelli, Francisca González, Francisca Urrutia, Diana Day, Lili Song, Yi Sui, Candice Delcourt, Thompson Robinson, Alice C. Durham, Ahtasam Ebraimo, Wan Asyraf Wan Zaidi, Stephen Jan, Richard I. Lindley, Victor C. Urrutia, Craig S. Anderson, the OPTIMISTmain Investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2024) 53 (5): 635–642.
Published Online: 26 October 2023
...; Wan Asyraf Wan Zaidi; Stephen Jan; Richard I. Lindley; Victor C. Urrutia; Craig S. Anderson; the OPTIMISTmain Investigators Introduction: Careful monitoring of patients who receive intravenous thrombolysis (IVT) for acute ischemic stroke (AIS) is resource-intensive, and potentially less relevant...
Journal Articles
Effect of Needle-To-Puncture Time on Reperfusion Outcome in Acute Ischemic Stroke
Available to PurchaseChih-Hao Chen, Fouzi Bala, Mohamed Najm, Ibrahim Alhabli, Nishita Singh, Nima Kashani, Rosalie V. McDonough, MacKenzie Horn, Jilian Stang, Andrew M. Demchuk, Bijoy K. Menon, Michael D. Hill, Mohammed A. Almekhlafi
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2024) 53 (2): 168–175.
Published Online: 26 July 2023
... between start of intravenous thrombolysis (IVT) to start of endovascular thrombectomy (EVT) on stroke outcomes. Methods: Data from the Quality Improvement and Clinical Research (QuICR) provincial stroke registry from Alberta, Canada, were used to identify stroke patients who received IVT and EVT from...
Journal Articles
Thrombolysis for Acute Wake-Up and Unclear-Onset Strokes with Alteplase at 0.6 mg/kg in Clinical Practice: THAWS2 Study
Available to PurchaseSohei Yoshimura, Masatoshi Koga, Takashi Okada, Manabu Inoue, Kaori Miwa, Mayumi Fukuda-Doi, Rei Kondo, Takeshi Inoue, Masahiko Ichijo, Masafumi Ohtaki, Yoshinari Nagakane, Ryo Itabashi, Nobuyuki Sakai, Kazumi Kimura, Kenji Kamiyama, Yoshiaki Shiokawa, Yoshiki Yagita, Toru Iwama, Yusuke Yakushiji, Masayoshi Kusumi, Tetsu Yamaki, Jyunichi Uemura, Asuka Yasuura, Shouhei Noshiro, Daiki Fukunaga, Yukako Yazawa, Junya Aoki, Masaaki Yoshikawa, Masafumi Ihara, Kazunori Toyoda, for the THAWS trial investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2024) 53 (1): 46–53.
Published Online: 01 June 2023
.... The safety outcomes were symptomatic intracranial hemorrhage (sICH) after thrombolysis, all-cause deaths, and all adverse events. The efficacy outcomes were favorable outcome defined as an mRS score of 0–1 or recovery to the same mRS score as the premorbid score, complete independence defined as an mRS score...
Journal Articles
Predictors of Early Neurological Improvement and Its Relationship to Thrombolysis Treatment and Long-Term Outcome in the WAKE-UP Study
Available to PurchaseSubject Area:
Cardiovascular System
, Karger e-Journal Backfile Collection 2023
, Neurology and Neuroscience
Marlene Heinze, Bastian Cheng, Tae-Hee Cho, Martin Ebinger, Matthias Endres, Jochen B. Fiebach, Jens Fiehler, Josep Puig, Robin Lemmens, Vincent Thijs, Keith W. Muir, Norbert Nighoghossian, Alina Königsberg, Märit Jensen, Ewgenia Barow, Iris Lettow, Salvador Pedraza, Claus Z. Simonsen, Christian Gerloff, Götz Thomalla
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2023) 52 (5): 560–566.
Published Online: 02 March 2023
... Gerloff; Götz Thomalla Introduction: The aims of this study were to evaluate the relationship of clinical and imaging baseline factors and treatment on the occurrence of early neurological improvement (ENI) in the WAKE-UP trial of MRI-guided intravenous thrombolysis in unknown onset stroke and to examine...
Journal Articles
Subject Area:
Cardiovascular System
, Karger e-Journal Backfile Collection 2023
, Neurology and Neuroscience
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2023) 52 (5): 597–606.
Published Online: 14 December 2022
...Yaowen Hu; Junhui Su; Xinxin Cui; Lizhen Pan; Lingjing Jin; Fei Teng When spontaneous cervical spinal epidural hematoma (SCEH) presents with hemiparesis, it can be misdiagnosed with ischemic stroke (IS), and the treatment of IS such as thrombolysis may deteriorate the symptoms of patients with SCEH...
Journal Articles
Cerebral Small Vessel Disease Burden and Futile Reperfusion after Endovascular Treatment for Patients with Acute Ischemic Stroke
Available to PurchaseSubject Area:
Cardiovascular System
, Karger e-Journal Backfile Collection 2023
, Neurology and Neuroscience
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2023) 52 (4): 427–434.
Published Online: 21 October 2022
... large artery occlusion, who were treated with EVT and achieved successful reperfusion (thrombolysis in cerebral infarction grade 2b–3). The cerebral SVD burden was evaluated using baseline brain magnetic resonance imaging using a modified Fazekas score (mFS). The main outcome variable was FR, defined...
Journal Articles
A Chilean Experience of Telestroke in a COVID-19 Pandemic Year
Available to PurchaseCarlos Delfino, Enrico Mazzon, Gabriel Cavada, Paula Muñoz Venturelli, Alejandro M. Brunser, Felipe Jurado Díaz, Lorena Lara Cisternas, Diego Rocha Jiménez, Mirya Arévalo Valdivia, Diego Rojas Torres, Eloy Mansilla
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2022) 51 (5): 690–694.
Published Online: 07 April 2022
..., thrombolysis rate, stroke severity, and time from the stroke onset to hospital admission. Results: We observed that the number of stroke codes and the number of patients undergoing reperfusion therapy did not change significantly ( p = 0.669 and 0.415, respectively). No differences were found with respect...
Journal Articles
Association of Elevated Body Mass Index with Functional Outcome and Mortality following Acute Ischemic Stroke: The Obesity Paradox Revisited
Available to PurchaseAlis J. Dicpinigaitis, Kieran E. Palumbo, Chirag D. Gandhi, Jared B. Cooper, Simon Hanft, Haris Kamal, Steven D. Shapiro, Eric Feldstein, Martin Kafina, Christeena Kurian, Ji Y. Chong, Stephan A. Mayer, Fawaz Al-Mufti
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2022) 51 (5): 565–569.
Published Online: 14 February 2022
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acute ischemic stroke Obesity Thrombectomy Thrombolysis Outcome Obesity has traditionally been considered a poor determinant of health [1]. In the context...
Journal Articles
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2021) 50 (6): 666–680.
Published Online: 14 October 2021
..., instructions or products referred to in the content or advertisements. 2021 Stroke History Cerebral blood flow Neuroprotection Thrombolysis Mobile stroke unit NIH “Until today, stroke was an untreatable disease” [ 1 ]. Those were my words to the press on December 14, 1995, when...
Journal Articles
Contemporary Trends in the Treatment of Mild Ischemic Stroke with Intravenous Thrombolysis: Paul Coverdell National Acute Stroke Program
Available to Purchase
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2022) 51 (1): 60–66.
Published Online: 17 August 2021
...Ganesh Asaithambi; Xin Tong; Sallyann M. Coleman King; Mary G. George Background: Presentation with mild symptoms is a common reason for intravenous thrombolysis (IVT) nonuse among acute ischemic stroke (AIS) patients. We examined the impact of IVT on the outcomes of mild AIS over time. Methods...
Journal Articles
Disparities between Asian and Non-Asian Thrombolyzed Acute Ischemic Stroke Patients in the Enhanced Control of Hypertension and Thrombolysis Stroke Trial
Available to PurchaseChen Chen, Xia Wang, Xiaoying Chen, Menglu Ouyang, Lingli Sun, Hisatomi Arima, Thompson Robinson, Richard I. Lindley, John Chalmers, Gang Li, Lili Song, Craig S. Anderson, for the ENCHANTED Investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2021) 50 (5): 560–566.
Published Online: 21 June 2021
... profile and management approaches, we aimed to determine disparities in clinical outcomes between Asian and non-Asian participants of the international, Enhanced Control of Hypertension and Thrombolysis Stroke study (ENCHANTED). Methods: ENCHANTED was a multicenter, prospective, partial-factorial...
Journal Articles
Felix Schlachetzki, Sibylle Wilfling, Nikolai Dominik Hubert, Andrea Wagner, Roman L. Haberl, Ralf Andreas Linker, Gordian Jan Hubert
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2021) 50 (3): 317–325.
Published Online: 04 February 2021
... (IS) and related consultations using the telestroke TEMPiS “working diagnosis” database prior (PL), within (WL), and after easing (EL) of CPL. Methods: Twelve hospitals were selected and data analyzed regarding IS (including intravenous thrombolysis [intravenous recombinant tissue plasminogen; IV rtPA...
Journal Articles
Vascular Occlusion Evolution in Endovascular Reperfusion Candidates Transferred from Primary to Comprehensive Stroke Centers
Available to PurchaseAlan Flores, Xavier Ustrell, Laia Seró, Anna Pellisé, Paula Rodriguez, Jaume Viñas, Marc Ribó, Jurek Krupinski, Natalia Más, Sonia Garcia, Ernesto Palomeras Soler, Dolores Cocho, David Canovas, Francisco Purroy, Joaquim Serena, Jose Zaragoza-Brunet, Victor Obach, Natalia Perez de la Ossa, Pere Cardona, Carlos A. Molina, Sonia Abilleira, Marta Rubiera, on behalf of Catalan Stroke Code and Reperfusion Consortium
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2020) 49 (5): 550–555.
Published Online: 22 October 2020
... practice . JAMA . 2019 ; 322 ( 3 ): 252 – 63 . 10.1001/jama.2019.8286 . 6. Seners P , Turc G , Maïer B , Mas JL , Oppenheim C , Baron JC . Incidence and predictors of early recanalization after intravenous thrombolysis: a systematic review and meta-analysis...
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