...Tae Jung Kim; Ji Sung Lee; Jae Sun Yoon; Mi Sun Oh; Ji-Woo Kim; Soo-Hyun Park; Kyung-Ho Yu; Byung-Chul Lee; Sang-Bae Ko; Byung-Woo Yoon Introduction: Although statin therapy reduces cardiovascular events, statin use is associated with the risk of new-onset diabetes mellitus (NODM). Using a linked...

... Salman; David Tirschwell; Joan Marti-Fabregas; Magdy Selim Introduction: The benefits and risks of HMG-CoA reductase inhibitor (statin) drugs in survivors of intracerebral hemorrhage (ICH) are unclear. Observational studies suggest an association between statin use and increased risk of lobar ICH...

...Ashkan Mowla; Harshit Shah; Navdeep Singh Lail; Caila B Vaughn; Peyman Shirani; Robert N. Sawyer Aim: The aim of this was to study the effects of statins and their intensity on symptomatic intracranial hemorrhage (sICH) and outcome after IV thrombolysis (IVT) for acute ischemic stroke (AIS...

...Clare Flach; Maria Elstad; Walter Muruet; Charles D.A. Wolfe; Anthony G. Rudd; Abdel Douiri Background: The benefit of statins on stroke incidence is well known. However, data on the relationship between pre- and post-stroke statin use, recurrence, and survival outcomes are limited. We aim...

... or transient ischemic attack. However, the role of statin in cardioembolic stroke is unclear. We investigated the association of statin with pretreatment collateral status in cardioembolic stroke. Methods: A collaborative study from two stroke centers in distinct geographic regions included consecutive...

... of stroke were age, prior stroke, prior coronary artery bypass surgery, anterior AMI and systolic blood pressure >190 mm Hg on presentation. Early administration of statins was independently associated with reduced stroke risk (odds ratio, OR, 0.4, 95% confidence interval, CI, 0.19–0.90, p = 0.025...

... assigned to a diet group (n = 20) or a statin group (atorvastatin; n = 20). Carotid plaques were monitored by measuring intima media thickness (IMT) and IBS values at baseline and after 6 months. Results: Three-dimensional IBS imaging showed that relative lipid volume of carotid plaques significantly...

...Muge Yemisci; Hakan Ay; Çetin Kocaefe; Jianhua Qui; Kamil Topalkara; Meral Özgüç; Şerafettin Kirazli; Osman Özcebe; Michael A. Moskowitz; Turgay Dalkara Background/Aims: Experimental studies suggest an enhanced endothelial and platelet nitric oxide (NO) generation after statin treatment, possibly...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Stroke prevention Hypertension Statin Antiplatelet therapy The concept of the polypill was developed in a 2003 editorial of the British Medical Journal, assuming...

... estimation in ischemic stroke is becoming important with recent trial results indicating the benefits of statins. We therefore aimed to determine the optimal time for lipid measurements after stroke. We hypothesized that TC would acutely decrease after stroke and return to baseline by 12 weeks. Methods...

...Pierre Amarenco; Philippa Lavallée; Pierre-Jean Touboul Four randomized trials with a statin and one trial with a fibrate showed a modest but significant absolute reduction in the incidence of stroke in patients with a previous myocardial infarction. The reasons for the positive effect of statins...

... Evidence suggests that statin therapy reduces the risk of stroke in patients with coronary heart disease (CHD), but its benefit for patients with cerebrovascular disease and no history of CHD remains uncertain. The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Study...