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Keywords: Sodium channel blocker
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Journal Articles
Cerebrovasc Dis (1998) 8 (1): 31–37.
Published Online: 16 January 1998
...Keith W. Muir; Steven J.C. Hamilton; Martin W. Lunnon; Stephen Hobbiger; Kennedy R. Lees Background: 619C89 is a use-dependent sodium channel blocker which reduces hemispheric infarction volume by up to 60% after permanent middle cerebral artery occlusion in rats. Intravenous doses of up to 1 mg/kg...