... January 2015 to December 2019. We assessed the impact of the time interval between IVT bolus to EVT puncture (needle-to-puncture times [NPT]) on outcomes. Radiological outcomes included successful initial recanalization (revised Arterial Occlusive Lesion 2b–3), successful initial and final reperfusion...

... completion. Hyperintense acute reperfusion injury marker was assessed on post-EVT pre-contrast fluid-attenuated inversion recovery at 24 h. Major early neurological improvement was defined as a reduction of the admission National Institutes of Health Stroke Scale by ≥8 points or a score of 0–1 at 24 h. Good...

... on acute cerebrovascular disease care across 9 comprehensive stroke centers throughout Los Angeles County (LAC). Methods: Volume of emergency stroke code activations, patient characteristics, stroke severity, reperfusion rates, treatment times, and outcomes from February 1 to April 30, 2020, were compared...

... thrombolysis (IVT) alone. However, rate, clinical outcome, and recanalization pattern of this phenomenon are poorly understood. Objectives and Methods: Patients with ELVO recanalized only by IVT were analyzed, and frequency of recanalization, clinical outcome, safety variables, and reperfusion pattern were...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Thrombectomy Stroke management Reperfusion Ischemic stroke Adverse event...

... of this study was to evaluate the impact of reperfusion on clinical outcome in low National Institutes of Health Stroke Scale (NIHSS) patients treated with MT. Methods: We analysed 138 consecutive patients with acute LVO of the anterior circulation (middle cerebral artery M1 or M2 segment, internal carotid...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acute stroke Middle cerebral artery occlusion Magnetic resonance imaging Reperfusion Recanalization In acute...

... management. The more sophisticated imaging-based selection, those assessing collateral blood flow or ischaemic penumbra appear to be associated with better outcomes and possibly fewer complications. The importance of achieving effective, quality reperfusion is also demonstrated, in a remarkably linear...

... treatment (EVT). We conducted a systematic review and meta-analysis to synthesize relevant evidence currently available. Methods: Relevant full-text articles published in English since January 1, 2000, reporting associations between collateral status and successful reperfusion and/or recanalization in acute...

...; Alicia C. Castonguay; Coleman Martin; Nils Mueller-Kronast; Joey D. English; Italo Linfante; Timothy W. Malisch; Rishi Gupta Background: There are multiple clinical and radiographic factors that influence outcomes after endovascular reperfusion therapy (ERT) in acute ischemic stroke (AIS). We sought...

... hemorrhage-associated pneumonia. Markers such as monocyte human leukocyte antigen-DR expression might help target those at greatest risk. Hypothermia Reperfusion Stem cell therapy Stroke Biomarkers Cerebral reorganization Immunology © 2012 S. Karger AG, Basel 2012 Copyright / Drug...

... in humans, a chance of recovery existed if collateral perfusion developed spontaneously within the first hours. In transient MCAO, reperfusion was only effective in preventing infarction when it was initiated as long as misery perfusion persisted; in these cases tissue was salvaged and large infarcts did...

...J. Rudolf; M. Grond; C. Stenzel; M. Neveling; W.-D. Heiss Whether ‘malignant’ brain edema following ischemic stroke is due to or aggravated by reperfusion and therefore more frequent after thrombolytic therapy of stroke is still under debate. From 3/96 to 1/97, we treated 51 patients with acute...

...J. Grotta Multi-modality therapy for acute ischaemic stroke is an emerging concept stimulated by the existing vacuum in stroke treatment and an increasing understanding of the ischaemic cascade. Experimental studies have shown that infarct size can be reduced more by combinations of reperfusion...

... axis. Post-treatment angiography (immediately after completion of infusion) demonstrated complete and >50% reperfusion in 10 of 47 patients (21.3%) treated with rt-PA and 2 of 46 patients (4.3%) treated with placebo (p = 0.034). The outcome 4 weeks after onset was significantly better in the rt-PA...

... velocity in the symptomatic middle cerebral artery did not increase in the first 5 days after symptom onset (implying no early reperfusion) the odds of severe infarct swelling were increased 7.6-fold (95% confidence interval 1.2- to 46.4-fold, 2p = 0.03), and the odds of a poor clinical outcome (dead...