... the evolution of perihaematomal oedema (PHO) >24 h after ICH onset. We aimed to determine the trajectory of PHO after ICH onset and its association with outcome. Methods: We did a prospective cohort study using a pre-specified scanning protocol in adults with first-ever spontaneous ICH and measured absolute...

... recurrence, functional and cognitive outcomes, and quality of life. Methods: The SATURN trial is a multi-center, pragmatic, prospective, randomized, open-label, phase III clinical trial with blinded end-point assessment. A planned total of 1,456 patients with lobar ICH will be recruited from 140 sites...

... Guo; for CHAIN investigators Introduction: The popular traditional Chinese medicine (TCM) compound FYTF-919 (Zhong Feng Xing Nao prescription) may improve outcome from acute intracerebral hemorrhage (ICH) through effects on brain edema, hematoma absorption, and the immune system. This study...

... between start of intravenous thrombolysis (IVT) to start of endovascular thrombectomy (EVT) on stroke outcomes. Methods: Data from the Quality Improvement and Clinical Research (QuICR) provincial stroke registry from Alberta, Canada, were used to identify stroke patients who received IVT and EVT from...

...Sritheja Reddy; Naveen Kumar Paramasivan; Sapna Erat Sreedharan; Sajith Sukumaran; Jissa Vinoda Thulaseedharan; Padmavathy N. Sylaja Introduction: Elevated admission blood pressure (BP) and BP variability have been shown to be associated with poor outcomes in most studies, while few studies have...

... the association of ENI with long-term favorable outcome in patients treated with intravenous thrombolysis. Methods: We analyzed data from all patients with at least moderate stroke severity, reflected by an initial National Institutes of Health Stroke Scale (NIHSS) score ≥4 randomized in the WAKE-UP trial. ENI...

...Takuya Kiyohara; Yasuhiro Kumai; Tomohiro Yubi; Eiichi Ishikawa; Yoshinobu Wakisaka; Tetsuro Ago; Takanari Kitazono Background: Little is known about the association between poststroke cognitive impairment (PSCI) and functional outcome in the acute care phase of ischemic stroke and the influence...

... outcomes in many diseases. However, data regarding the impact of the SHR on ischaemic stroke, especially in young adults, are limited. Therefore, the aim of this study was to investigate whether the SHR is associated with stroke severity and adverse outcomes in young adults with ischaemic stroke...

... outcomes remain uncertain. Additionally, admission hyperglycemia quite frequently accompanies AIS patients, which is associated with unfavorable outcome. Thus, we aimed to investigate the effects of hyperferritinemia on 3-month and 1-year functional outcomes in AIS patients and especially those...

... the association with functional outcomes in patients with intracerebral hemorrhage (ICH). Methods: We conducted a prospective cohort study of consecutive acute ICH patients. The stroke severity at onset and hospital admission was assessed using the Chongqing Stroke Scale (CQSS), and prehospital UND was defined...

..., the relationship between ONSD and prognosis of ICH is uncertain. This study aimed to investigate the predictive value of ONSD on poor outcome of patients with acute spontaneous ICH. Methods: We studied 529 consecutive patients with acute spontaneous ICH who underwent initial CT within 6 h of symptom onset between...

... ischemic stroke (AIS) patients with elevated body mass indices (BMIs), a phenomenon termed the “obesity paradox.” Objective: The aim of this study was to evaluate the independent association between obesity and clinical outcomes following AIS. Methods: Weighted discharge data from the National Inpatient...

... with more recent systems to deliver hyper-acute stroke interventions and implementing stroke units in lower resource regions. [email protected] 26 05 2021 17 06 2021 21 9 2021 Stroke unit Outcome Systematic review Randomized trial © 2021 The Author(s...

...Xing Wang; Yu Zhang; Lu Jia; Tiangui Li; Chao You; Fang Fang Objective: The relationship between smoking and clinical outcomes after aneurysmal subarachnoid hemorrhage (aSAH) is poorly clarified, and current pieces of evidence are inconsistent. The purpose of this multicenter cohort study...

...Chen Chen; Xia Wang; Xiaoying Chen; Menglu Ouyang; Lingli Sun; Hisatomi Arima; Thompson Robinson; Richard I. Lindley; John Chalmers; Gang Li; Lili Song; Craig S. Anderson; for the ENCHANTED Investigators Background and Purpose: As outcomes for acute ischemic stroke (AIS) vary according to clinical...

... for nonparticipation and other missing data. The median age of the 294 individuals was 70 years (IQR 60–79), 4% were black, and 52% were female (Table  1 ). Table 1. Demographics and stroke risk factors of the 2015 ischemic stroke outcome cohort by outcome data availability Agreement between EMR...

... with primary ICH. Methods: An ICH was considered minor if associated with a favorable 3-month outcome (modified Rankin Scale score ≤2). For supratentorial ICH, the discovery cohort consisted of 478 patients prospectively admitted at University Hospital del Mar. Association between NIHSS at admission and 3...

... outcome of AIS in the course of COVID-19 remains unknown. We compared early clinical outcome and mortality of COVID-positive (+) patients admitted for AIS with COVID-negative (−) ones. We hypothesized that COVID+ patients would have poorer clinical outcomes and present a higher rate of TEs and mortality...

... the risk of hemorrhage during pregnancy, and there are no standard guidelines for the management of pregnant women who present with BAVM rupture. The purpose of this study is to describe maternal and fetal outcomes and treatment strategies in patients with BAVM hemorrhage during pregnancy. Methods: We...

...Maria Daniela Zambrano Espinoza; Navdeep Singh Lail; Caila B. Vaughn; Peyman Shirani; Robert N. Sawyer; Ashkan Mowla Background: We sought to investigate the effect of obesity and BMI on functional outcome and rate of symptomatic intracranial hemorrhage (sICH) in a large sample of patients...