... improvement. Findings in the last 15 years suggest that stroke and related injury create a cerebral milieu similar to that of early brain development, a period characterized by rapid neuronal growth and neuroplasticity. A variety of interventions (e.g., stem cells, delivery of growth factors) are currently...

... of evidence-based treatment options. NeuroAiD is a traditional Chinese medicine that has been shown to induce neuroplasticity, promote cell proliferation and stimulate the development of dense axonal and dendritic networks in animal stroke models. NeuroAiD may improve cerebral blood flow and functional...

... for 10 days. Motor recovery was evaluated by the grip strength test. The brain lesion was assessed by cresyl violet and NeuN staining 5 weeks after stroke. Expression of neuroplasticity-related genes ( GAP43, c- jun , neurocan and ephrin B1) was analyzed by Taqman real-time PCR. Results: GHB-treated mice...

... limitations restrict use to a small proportion of patients. Although a wide range of neuroprotective substances has been effective in experimental models, they have repeatedly failed in clinical trials because of toxicity or loss of effectiveness. Recent strategies based on neuroplasticity and cellular...

..., functional recovery may continue over subsequent days and months due, mainly, to the activation of neuroplasticity mechanisms [ 25 ]. Recent advances in the understanding of mechanisms involved in the endogenous processes of functional recovery, and in the potential of cell therapy, have created new options...