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Keywords: Lacunes
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Journal Articles
Journal Articles
Cerebrovasc Dis (2022) 51 (2): 131–137.
Published Online: 21 February 2022
... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cerebral small-vessel disease Lacunes...
Journal Articles
Journal Articles
Cerebrovasc Dis (2014) 37 (5): 382–388.
Published Online: 26 June 2014
... of 3.4 years. The presence of microbleeds and lacunes was visually rated by trained research physicians, and white matter lesions (WMLs) were automatically segmented at both time points. Logistic regression was used to investigate the association of microbleeds with incident lacunes, and linear...
Journal Articles
Cerebrovasc Dis (2012) 34 (5-6): 336–342.
Published Online: 14 November 2012
... visible on MR imaging (median volume 2.05 ml, IQR 0.88–8.88) and 7 of the 33 had old lacunes at baseline: WML volume was 8.54 ml (IQR 5.86–15.80) excluding versus 10.98 ml (IQR 6.91–24.86) including ISL (p < 0.001). At follow-up, median 39 months later (IQR 30–45), 3 patients had a de novo stroke...
Journal Articles
Cerebrovasc Dis (2009) 28 (2): 151–156.
Published Online: 17 June 2009
... be of value. We sought to determine the occurrence of MRI perfusion-weighted imaging (PWI) abnormalities in lacunes, and whether they help predict clinical and radiological outcome. Methods: Patients with lacunar stroke or TIA were selected from a prospective MR imaging study. MRI was performed within 24 h...
Journal Articles
Cerebrovasc Dis (2008) 26 (2): 113–119.
Published Online: 17 June 2008
... are produced by microglia [ 18 ] and may contribute to white matter dysfunction and long-term cognitive decline [ 17 ], but might also be necessary for tissue adjustments and repair mechanisms. Stroke Matrix metalloproteinases Lacunes Small vessel disease The matrix metalloproteinases (MMP...
Journal Articles
Cerebrovasc Dis (2002) 13 (Suppl. 2): 58–60.
Published Online: 15 March 2002
... dementia with lacunes? Neurology 1986;36:340–345. 24. Erkinjuntti T: Types of multi-infarct dementia. Acta Neurol Scand 1987;75:391–399. 25. Mahler ME, Cummings JL: The behavioural neurology of multi-infarct dementia. Alzheimer Dis Assoc Disord 1991;5:122–130. 26. Cummings JL: Fronto...
Journal Articles
Cerebrovasc Dis (2002) 13 (Suppl. 2): 7–10.
Published Online: 15 March 2002
... with a determined genetic origin. It is possible that other genetic factors contribute, by interaction with conventional risk factors, to the development of white matter injury in nonfamilial cases. 15 3 2002 Lacunes Small vessel disease White matter lesions © 2002 S. Karger AG, Basel 2002...
Journal Articles
Cerebrovasc Dis (2002) 13 (Suppl. 2): 1–6.
Published Online: 15 March 2002
.... This entity vanished as arterial hypertension became established with the introduction of the sphygmomanometer (1905). Before the 19th century, apoplexy was considered a uniformly fatal disease, although Willis first recognized post-stroke dementia in 1672. Dechambre (1838) first reported ‘lacunes’ in stroke...
Journal Articles
Cerebrovasc Dis (2002) 13 (Suppl. 2): 11–15.
Published Online: 15 March 2002
... matter Histopathology Ischemia Incomplete infarct Lacunes Angiopathy In vascular cognitive impairment, or vascular dementia (VaD), white matter lesions (WML) constitute a major portion of the pathology seen in the brain. The gray matter is variably involved and may be spared, but a case...
Journal Articles
Journal Articles
Cerebrovasc Dis (1992) 2 (2): 87–92.
Published Online: 08 April 1992
... and atherosclerosis of larger leptomeningeal arteries; (ii) widespread bilateral incomplete lesions of hemispheric white matter and multiple lacunes supratentorially in the centrum semiovale, the striatum, the thalamus, the internal capsule, and, to a lesser extent infratentorially; (iii) widening of the lateral...