...Xin Jiang; Lizhang Chen; Jian Wang; Jinghuan Fang; Mengmeng Ma; Muke Zhou; Hongbo Zheng; Fayun Hu; Dong Zhou; Li He Introduction: Selective endovascular brain hypothermia has been proposed as a potential neuroprotective strategy; however, its effectiveness is still not well established. The primary...

...Wei Xu; Xiaokun Geng; Aminah I. Fayyaz; Yuchuan Ding Background: Acute ischemic stroke remains a major contributor to mortality and disability worldwide. The use of hypothermia has emerged as a promising neuroprotective strategy, with proven effectiveness in cardiac arrest and neonatal hypoxic...

...Joji B. Kuramatsu; Rainer Kollmar; Stefan T. Gerner; Dominik Madžar; Andrea Pisarčíková; Dimitre Staykov; Stephan P. Kloska; Arnd Doerfler; Ilker Y. Eyüpoglu; Stefan Schwab; Hagen B. Huttner Background: Therapeutic hypothermia (TH) is an established treatment after cardiac arrest and growing...

...-analyses and systematic reviews give no firm support for a beneficial effect of hypothermia on mortality and outcome after trauma. A number of issues in this field are still unresolved, including depth and duration of hypothermia. The situation is better for hypothermia after cardiac arrest. According...

... Hypothermia Cooling cap Cooling Stroke This study was approved by the local ethics committee of the Medical Faculty, University of Erlangen-Nuremberg. The head and neck cooling device (HVM Medical, Rothenburg, Germany) contains free-floating cooling gel with a central portion, covering the head...

...) induced hypothermia, targeting core body temperatures below 36.5°C. A limited number of studies investigated antipyretic strategies after acute stroke and their results were rather disappointing in terms of clinical efficacy. For that reason, it remains unproven, whether sufficient fever treatment...

...Isabelle Korn-Lubetzki; Israel Steiner; Avraham Oren; Rachel Tauber; Bettina Steiner-Birmanns; Daniel Bitran Background: The effect of hypothermia as a possible neuroprotective tool on the outcome of cardiac surgery is still controversial. Methods: We retrospectively assessed all patients who...

...Pilar Delgado; Juan Sahuquillo; M. Antonia Poca; José Álvarez-Sabin Massive unilateral hemispheric infarction often develops progressive postischemic edema that leads to a malignant course of stroke with mortality of up to 80% with conventional medical therapies. Hypothermia and decompressive...

...Thomas Els; Eckard Oehm; Sabine Voigt; Joachim Klisch; Andreas Hetzel; Jan Kassubek Introduction: Both for hemicraniectomy and for hypothermia, several reports describe a beneficial effect in patients with malignant supratentorial cerebral ischemia. We compared the safety and the clinical outcome...

... may be therapeutic hypothermia, which has been found to be neuroprotective in animal models, as well as in clinical studies after cardiac arrest. Experience in stroke patients suggest that hypothermia may offer a new approach for the treatment of acute cerebral ischemia. Brain edema Hypothermia...

... changes in the extracellular space using microdialysis in a patient with left-sided hemispheric infarction treated with moderate hypothermia (33°C). Microdialysis probes were obtained from the infarcted and noninfarcted hemisphere during hypothermia and rewarming. Concentrations of extracellular...

... glucose Body temperature Hypothermia Acute treatment The prognosis of the stroke patient is determined by an interplay of factors such as initial stroke severity, age, and various comorbidities – factors difficult to modify. We have previously examined in the Copenhagen Stroke Study...