..., instructions or products referred to in the content or advertisements. 2024 Acute stroke Clinical trial Ambulance Hypertension Statistical analysis plan Timely treatment of acute stroke is important for both intracerebral hemorrhage (ICH) and acute ischemic stroke (AIS) [ 1‒3 ]. Continuous...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2022 Intracerebral hemorrhage Stroke Clinical trial Hypertension Cluster Statistical analysis plan This study is jointly funded by the Department for International...

...Alastair John Stewart Webb; Karolina A. Wartolowska; Linxin Li; Sara Mazzucco; Peter M. Rothwell Objective: Arterial stiffness, cerebral pulsatility, and beat-to-beat blood pressure variability partly mediate the relationship between hypertension and stroke, but it is unknown if these intermediate...

... stroke (AIS) patients. Methods: Prespecified analyses of the Enhanced Control of Hypertension and Thrombolysis Stroke Study for patients enrolled in both arms: (i) low-dose (0.6 mg/kg body weight) or standard-dose (0.9 mg/kg) alteplase and (ii) intensive (target systolic BP [SBP] 130–140 mm Hg...

... with Urgent Risk-factor Assessment and Improvement (SAMURAI)-ICH Study was a multicenter, prospective, observational study investigating the safety and feasibility of early (within 3 h from onset) reduction of systolic BP (SBP) to < 160 mm Hg with intravenous nicardipine for acute hypertension in cases...

... evident that vascular risk factors contribute to the development of cSVD and associated vascular cognitive impairment (VCI). Among them, hypertension emerged as such a major modifiable risk factor since the brain presents an early target for organ damage due to changes in blood pressure (BP). Subsequently...

...) hyperintensities of presumed vascular origin, with a voxel-based quantitative analysis of (18F)-fluorodesoxyglucose positron emission tomography (FDG-PET) imaging. Methods: Sixty older hypertensive patients with subjective memory complaints (75 ± 5 years, 34 women) were prospectively referred to FDG-PET and MRI...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Intracerebral hemorrhage Hypertension Blood pressure Acute stroke care Clinical trials Stroke patients who were admitted to the hospital on a weekend, in the night or during holidays...

...Ihab Hajjar; Vasilis Marmerelis; Dae C. Shin; Helena Chui Background: Hypertension is associated with cognitive deficits, particularly executive function, and decreased cerebral microvascular responsiveness to CO 2 (CO 2 vasoreactivity). The relation between CO 2 vasoreactivity and executive...

... (BP) reduction may attenuate hematoma expansion. ACCELERATE (the Evaluation of Patients with Acute Hypertension and Intracerebral Hemorrhage with Intravenous Clevidipine Treatment) is a pilot study representing the first evaluation of safety and efficacy of intravenous clevidipine for the rapid...

...Ursula G. Schulz; Rebecca H. Mason; Sonya E. Craig; Sally Howard; Deborah J. Nicoll; Malcolm Kohler; Peter M. Rothwell; John R. Stradling Background: Obstructive sleep apnoea (OSA) is associated with hypertension, nocturnal blood pressure (BP) surges, and increased risk of stroke. It may therefore...

... hypertension has been shown to reduce the cerebrovascular adaptation to BP variations. However, it is still unknown whether CA is impaired in chronic hypertension. This study evaluated whether a strict control of BP affects the CA in patients with chronic hypertension, and compared a valsartan-based regimen...

... study was to determine whether blood pressure-lowering therapy with the combination of the angiotensin receptor blocker losartan plus hydrochlorothiazide (LPH) worsens brain perfusion in patients with both hypertension and cerebral hemodynamic impairment due to symptomatic chronic major cerebral artery...

... with appropriate parameters was effective and safe in a normotensive rat model of thromboembolic middle cerebral artery occlusion (MCAO) stroke. The goal of this study was to test the safety of this strategy in a spontaneously hypertensive rat (SHR) model of permanent MCAO. Methods: Right MCAO was achieved in male...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Atorvastatin N-nitro- L -arginine-methyl ester Nitric oxide inhibition Hypertension Albuminuria Caveolin 1 Vascular endothelial growth factor RhoA ...

...-center experience, we found that MSICH account for 5.6% of all spontaneous ICH. Prior microhemorrhage burden, perhaps due to severity of hypertension or cerebral amyloid angiopathy, may mark those at risk for primary MSICH occurrence. The condition may be under-detected and under-reported if small...

...Marek Sykora; Jennifer Diedler; Sven Poli; Andre Rupp; Peter Turcani; Thorsten Steiner Background: Acute hypertension frequently occurs in acute stroke and is associated with unfavorable outcome. However, despite the high prevalence, the pathophysiology remains unclear. Baroreflex dysfunction has...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Positional ischemia Hypertension Postural stroke Orthostatic hypotension Cerebrovasc Dis 1995;5:313-314 Positional Cerebral Ischemia Alexandre...

... is strongly related to the frequent association of diabetes mellitus with other risk factors in the same individual, such as hypertension, obesity and hyperlipidemia. Diabetes mellitus has also been shown to be an independent predictor for hemorrhagic conversion of a cerebral infarction. However, its...

... of factors such as hypertension, cigarette smoking, alcohol consumption, diabetes mellitus and family history of aSAH in a South Indian population. The population-attributable risk (PAR) of smoking, hypertension and alcohol use was estimated for the South Indian as well as for the general Indian population...